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A calcium-sensing MCTP1/FYN/MEF2C circuit drives therapy-induced neuroendocrine prostate cancer.

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Title: A calcium-sensing MCTP1/FYN/MEF2C circuit drives therapy-induced neuroendocrine prostate cancer.
Authors: Dung PVT; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan., Chen WY; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 11031, Taiwan; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Liu MK; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan., Yeh SD; Department of Urology and Oncology, Taipei Medical University Hospital, Taipei 11031, Taiwan; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Prostate Center of Excellence, Taipei Medical University Hospital, Taipei 11031, Taiwan., Kajla G; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan., Yeh HL; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan., Chen WH; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan., Jiang KC; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan., Li HR; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan., Chen CS; School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Beltran H; Department of Medical Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA 02215-5450, USA., Wen YC; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Department of Urology, Wan Fang Hospital, Taipei Medical University, Taipei 11031, Taiwan; TMU Research Center of Urology and Kidney, Taipei Medical University, Taipei 11031, Taiwan. Electronic address: 95207@w.tmu.edu.tw., Liu YN; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan; Prostate Center of Excellence, Taipei Medical University Hospital, Taipei 11031, Taiwan. Electronic address: liuy@tmu.edu.tw.
Source: Neoplasia (New York, N.Y.) [Neoplasia] 2026 Jan; Vol. 71, pp. 101251. Date of Electronic Publication: 2025 Nov 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100886622 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5586 (Electronic) Linking ISSN: 14765586 NLM ISO Abbreviation: Neoplasia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A calcium-sensing MCTP1/FYN/MEF2C circuit drives therapy-induced neuroendocrine prostate cancer.
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  Data: <searchLink fieldCode="AU" term="%22Dung+PVT%22">Dung PVT</searchLink>; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+WY%22">Chen WY</searchLink>; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 11031, Taiwan; Department of Pathology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+MK%22">Liu MK</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+SD%22">Yeh SD</searchLink>; Department of Urology and Oncology, Taipei Medical University Hospital, Taipei 11031, Taiwan; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Prostate Center of Excellence, Taipei Medical University Hospital, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kajla+G%22">Kajla G</searchLink>; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+HL%22">Yeh HL</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+WH%22">Chen WH</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Jiang+KC%22">Jiang KC</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+HR%22">Li HR</searchLink>; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CS%22">Chen CS</searchLink>; School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.<br /><searchLink fieldCode="AU" term="%22Beltran+H%22">Beltran H</searchLink>; Department of Medical Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA 02215-5450, USA.<br /><searchLink fieldCode="AU" term="%22Wen+YC%22">Wen YC</searchLink>; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan; Department of Urology, Wan Fang Hospital, Taipei Medical University, Taipei 11031, Taiwan; TMU Research Center of Urology and Kidney, Taipei Medical University, Taipei 11031, Taiwan. Electronic address: 95207@w.tmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Liu+YN%22">Liu YN</searchLink>; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, New Taipei City 235, Taiwan; Prostate Center of Excellence, Taipei Medical University Hospital, Taipei 11031, Taiwan. Electronic address: liuy@tmu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22100886622%22">Neoplasia (New York, N.Y.)</searchLink> [Neoplasia] 2026 Jan; Vol. 71, pp. 101251. <i>Date of Electronic Publication: </i>2025 Nov 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100886622 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5586 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214765586%22">14765586 </searchLink><i>NLM ISO Abbreviation: </i>Neoplasia <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.neo.2025.101251
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              Text: 2026 Jan
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