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Predictive factors for the efficacy of brolucizumab in refractory polypoidal choroidal vasculopathy following aflibercept resistance.

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Title: Predictive factors for the efficacy of brolucizumab in refractory polypoidal choroidal vasculopathy following aflibercept resistance.
Authors: Yoshinaga A; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.; Department of Ophthalmology and Showa General Hospital, Hanakoganei, Kodaira, Tokyo, Japan., Kitamoto K; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan., Aoki S; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan., Terao R; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan., Inoue T; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.; Department of Ophthalmology and Micro-Technology, Yokohama City University School of Medicine, 4-57 Urafune-cho, Minami-ku, Yokohama, Kanagawa, Japan., Obata R; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.; Department of Ophthalmology and Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo, Japan., Azuma K; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Source: PloS one [PLoS One] 2025 Nov 04; Vol. 20 (11), pp. e0326018. Date of Electronic Publication: 2025 Nov 04 (Print Publication: 2025).
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Predictive factors for the efficacy of brolucizumab in refractory polypoidal choroidal vasculopathy following aflibercept resistance.
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  Data: <searchLink fieldCode="AU" term="%22Yoshinaga+A%22">Yoshinaga A</searchLink>; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.; Department of Ophthalmology and Showa General Hospital, Hanakoganei, Kodaira, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kitamoto+K%22">Kitamoto K</searchLink>; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Aoki+S%22">Aoki S</searchLink>; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Terao+R%22">Terao R</searchLink>; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Inoue+T%22">Inoue T</searchLink>; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.; Department of Ophthalmology and Micro-Technology, Yokohama City University School of Medicine, 4-57 Urafune-cho, Minami-ku, Yokohama, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Obata+R%22">Obata R</searchLink>; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.; Department of Ophthalmology and Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Azuma+K%22">Azuma K</searchLink>; Department of Ophthalmology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2025 Nov 04; Vol. 20 (11), pp. e0326018. <i>Date of Electronic Publication: </i>2025 Nov 04 (<i>Print Publication: </i>2025).
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