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HER2DX in older patients with HER2-positive early breast cancer: extended follow-up from the RESPECT trial of trastuzumab ± chemotherapy.

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Title: HER2DX in older patients with HER2-positive early breast cancer: extended follow-up from the RESPECT trial of trastuzumab ± chemotherapy.
Authors: Nozawa K; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.; Department of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Sawaki M; Department of Breast Oncology, Nagoya Medical Center, Nagoya, Japan., Uemura Y; Biostatistics Section, Department of Data Science, Center of Clinical Sciences, National Center for Global Health and Medicine, Shinjuku, Japan., Tsuneizumi M; Department of Breast Surgery, Shizuoka General Hospital, Shizuoka, Japan., Takano T; Department of Breast Medical Oncology, The Cancer Institute Hospital of JFCR, Koto, Japan., Gondo N; Department of Breast and Thyroid Surgical Oncology, Sagara Hospital, Kagoshima, Japan., Hara F; Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan., Harao M; Department of Breast Oncology, Jichi Medical University, Shimotsuke, Japan., Toyama T; Department of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Taira N; Department of Breast and Thyroid Surgery, Kawasaki Medical School, Kurashiki, Japan., Vivancos A; Reveal Genomics, Barcelona, Spain., Perou CM; Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA., Sanfeliu E; Reveal Genomics, Barcelona, Spain., Brasó-Maristany F; Reveal Genomics, Barcelona, Spain., Parker JS; Reveal Genomics, Barcelona, Spain., Buckingham W; Reveal Genomics, Barcelona, Spain., Paré L; Reveal Genomics, Barcelona, Spain., Villacampa G; Statistics Unit, Vall d'Hebron Institute of Oncology, Barcelona, Spain., Marín-Aguilera M; Reveal Genomics, Barcelona, Spain., Villagrasa P; Reveal Genomics, Barcelona, Spain., Prat A; Reveal Genomics, Barcelona, Spain. alprat@clinic.cat.; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain. alprat@clinic.cat.; Department of Medical Oncology, Clínic Barcelona Comprehensive Cancer Center, Barcelona, Spain. alprat@clinic.cat.; Breast Cancer Unit, IOB-QuirónSalud, Barcelona, Spain. alprat@clinic.cat.; Department of Medicine, University of Barcelona, Barcelona, Spain. alprat@clinic.cat., Iwata H; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Source: Nature communications [Nat Commun] 2025 Nov 04; Vol. 16 (1), pp. 9585. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HER2DX in older patients with HER2-positive early breast cancer: extended follow-up from the RESPECT trial of trastuzumab ± chemotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Nozawa+K%22">Nozawa K</searchLink>; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.; Department of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Sawaki+M%22">Sawaki M</searchLink>; Department of Breast Oncology, Nagoya Medical Center, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Uemura+Y%22">Uemura Y</searchLink>; Biostatistics Section, Department of Data Science, Center of Clinical Sciences, National Center for Global Health and Medicine, Shinjuku, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuneizumi+M%22">Tsuneizumi M</searchLink>; Department of Breast Surgery, Shizuoka General Hospital, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Takano+T%22">Takano T</searchLink>; Department of Breast Medical Oncology, The Cancer Institute Hospital of JFCR, Koto, Japan.<br /><searchLink fieldCode="AU" term="%22Gondo+N%22">Gondo N</searchLink>; Department of Breast and Thyroid Surgical Oncology, Sagara Hospital, Kagoshima, Japan.<br /><searchLink fieldCode="AU" term="%22Hara+F%22">Hara F</searchLink>; Department of Breast Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Harao+M%22">Harao M</searchLink>; Department of Breast Oncology, Jichi Medical University, Shimotsuke, Japan.<br /><searchLink fieldCode="AU" term="%22Toyama+T%22">Toyama T</searchLink>; Department of Breast Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Taira+N%22">Taira N</searchLink>; Department of Breast and Thyroid Surgery, Kawasaki Medical School, Kurashiki, Japan.<br /><searchLink fieldCode="AU" term="%22Vivancos+A%22">Vivancos A</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Perou+CM%22">Perou CM</searchLink>; Department of Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sanfeliu+E%22">Sanfeliu E</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Brasó-Maristany+F%22">Brasó-Maristany F</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Parker+JS%22">Parker JS</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Buckingham+W%22">Buckingham W</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Paré+L%22">Paré L</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Villacampa+G%22">Villacampa G</searchLink>; Statistics Unit, Vall d'Hebron Institute of Oncology, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Marín-Aguilera+M%22">Marín-Aguilera M</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Villagrasa+P%22">Villagrasa P</searchLink>; Reveal Genomics, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Prat+A%22">Prat A</searchLink>; Reveal Genomics, Barcelona, Spain. alprat@clinic.cat.; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain. alprat@clinic.cat.; Department of Medical Oncology, Clínic Barcelona Comprehensive Cancer Center, Barcelona, Spain. alprat@clinic.cat.; Breast Cancer Unit, IOB-QuirónSalud, Barcelona, Spain. alprat@clinic.cat.; Department of Medicine, University of Barcelona, Barcelona, Spain. alprat@clinic.cat.<br /><searchLink fieldCode="AU" term="%22Iwata+H%22">Iwata H</searchLink>; Department of Advanced Clinical Research and Development, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Nov 04; Vol. 16 (1), pp. 9585. <i>Date of Electronic Publication: </i>2025 Nov 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
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