Generation of exogenous kidneys via CRISPR/Cas9 mediated blastocyst complementation targeting Osr1 gene in mice.
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| Title: | Generation of exogenous kidneys via CRISPR/Cas9 mediated blastocyst complementation targeting Osr1 gene in mice. |
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| Authors: | Yeh TY; Doctoral Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, 402, Taiwan., Chiu IM; Doctoral Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, 402, Taiwan.; Neuroscience and Brain Disease Center, China Medical University, Taichung, 404, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 404, Taiwan.; Department of Internal Medicine, The Ohio State University, Columbus, OH, 43210, USA., Huang YJ; Department of Animal Science and Technology, National Taiwan University, Taipei, 106, Taiwan., Wu SC; Department of Animal Science and Technology, National Taiwan University, Taipei, 106, Taiwan., Hsieh CC; National Laboratory Animal Center, National Applied Research Laboratories, Taipei, 115, Taiwan., Sung HH; National Laboratory Animal Center, National Applied Research Laboratories, Taipei, 115, Taiwan., Hwu WL; Center for Precision Medicine, China Medical University Hospital, Taichung, 404, Taiwan., Wang GJ; Doctoral Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, 402, Taiwan. gjwang@dragon.nchu.edu.tw.; Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, 402, Taiwan. gjwang@dragon.nchu.edu.tw.; Department of Mechanical Engineering, National Chung Hsing University, Taichung, 402, Taiwan. gjwang@dragon.nchu.edu.tw., Ju JC; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 404, Taiwan. jcju@dragon.nchu.edu.tw.; Center for Precision Medicine, China Medical University Hospital, Taichung, 404, Taiwan. jcju@dragon.nchu.edu.tw.; Department of Animal Science, National Chung Hsing University, Taichung, 402, Taiwan. jcju@dragon.nchu.edu.tw. |
| Source: | Scientific reports [Sci Rep] 2025 Nov 04; Vol. 15 (1), pp. 38648. Date of Electronic Publication: 2025 Nov 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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