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Intra-host diversity of SARS-CoV-2 in children with long-term and short-term excretion in nasopharyngeal samples.

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Title: Intra-host diversity of SARS-CoV-2 in children with long-term and short-term excretion in nasopharyngeal samples.
Authors: Khemiri H; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia., Lorusso A; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy., Ayouni K; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia., Radomski N; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy., Khaled MB; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Mangone I; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy., Di Pasquale A; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy., Cammà C; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy., Ben Fraj I; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Mekki N; Laboratory of Transmission, Control and Immunobiology of Infection, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Meftah K; Laboratory of Microbiology Bechir Hamza Children's Hospital, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Souiai O; Laboratory of Bioinformatics, Biomathematics and Biostatistics, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia., Ben Mustapha I; Laboratory of Transmission, Control and Immunobiology of Infection, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Rekaya S; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Touzi H; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia., Sadraoui A; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia., Meddeb Z; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia., Hogga N; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia., Smaoui H; Laboratory of Microbiology Bechir Hamza Children's Hospital, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Barbouche MR; Laboratory of Transmission, Control and Immunobiology of Infection, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.; Department of Microbiology, Immunology and Infectious Diseases, College of Medicine and Health Sciences, Arabian Gulf University, Manama, Bahrain., Ouederni M; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Gdoura M; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia., Triki H; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia., Haddad-Boubaker S; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia. sondeshaddadboubaker@gmail.com.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia. sondeshaddadboubaker@gmail.com.
Source: BMC infectious diseases [BMC Infect Dis] 2025 Nov 04; Vol. 25 (1), pp. 1491. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intra-host diversity of SARS-CoV-2 in children with long-term and short-term excretion in nasopharyngeal samples.
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  Data: <searchLink fieldCode="AU" term="%22Khemiri+H%22">Khemiri H</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Lorusso+A%22">Lorusso A</searchLink>; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy.<br /><searchLink fieldCode="AU" term="%22Ayouni+K%22">Ayouni K</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Radomski+N%22">Radomski N</searchLink>; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy.<br /><searchLink fieldCode="AU" term="%22Khaled+MB%22">Khaled MB</searchLink>; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Mangone+I%22">Mangone I</searchLink>; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Pasquale+A%22">Di Pasquale A</searchLink>; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy.<br /><searchLink fieldCode="AU" term="%22Cammà+C%22">Cammà C</searchLink>; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise, Teramo, 64100, Italy.<br /><searchLink fieldCode="AU" term="%22Ben+Fraj+I%22">Ben Fraj I</searchLink>; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Mekki+N%22">Mekki N</searchLink>; Laboratory of Transmission, Control and Immunobiology of Infection, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Meftah+K%22">Meftah K</searchLink>; Laboratory of Microbiology Bechir Hamza Children's Hospital, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Souiai+O%22">Souiai O</searchLink>; Laboratory of Bioinformatics, Biomathematics and Biostatistics, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Ben+Mustapha+I%22">Ben Mustapha I</searchLink>; Laboratory of Transmission, Control and Immunobiology of Infection, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Rekaya+S%22">Rekaya S</searchLink>; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Touzi+H%22">Touzi H</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Sadraoui+A%22">Sadraoui A</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Meddeb+Z%22">Meddeb Z</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Hogga+N%22">Hogga N</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Smaoui+H%22">Smaoui H</searchLink>; Laboratory of Microbiology Bechir Hamza Children's Hospital, Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Barbouche+MR%22">Barbouche MR</searchLink>; Laboratory of Transmission, Control and Immunobiology of Infection, Institut Pasteur de Tunis, University of Tunis El Manar, Tunis, Tunisia.; Department of Microbiology, Immunology and Infectious Diseases, College of Medicine and Health Sciences, Arabian Gulf University, Manama, Bahrain.<br /><searchLink fieldCode="AU" term="%22Ouederni+M%22">Ouederni M</searchLink>; Department of Pediatrics: Immunohematology and stem cell transplantation, National Center of Bone Marrow Transplantation, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Gdoura+M%22">Gdoura M</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Triki+H%22">Triki H</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia.; Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.<br /><searchLink fieldCode="AU" term="%22Haddad-Boubaker+S%22">Haddad-Boubaker S</searchLink>; Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for the EMR, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia. sondeshaddadboubaker@gmail.com.; Research Laboratory 'Virus, Vectors and Hosts: One Health Approach and Technological Innovation for a Better Health' LR20IPT02, Institut Pasteur de Tunis, University Tunis El Manar, Tunis, Tunisia. sondeshaddadboubaker@gmail.com.
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