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Danggui Shaoyao San attenuates depressive-like behaviors in mice via TLR4/NF-κB p65/JAK-STAT3/AKT-GSK3β signaling pathways: modulation of hippocampal neurogenesis and neuroinflammation.

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Title: Danggui Shaoyao San attenuates depressive-like behaviors in mice via TLR4/NF-κB p65/JAK-STAT3/AKT-GSK3β signaling pathways: modulation of hippocampal neurogenesis and neuroinflammation.
Authors: Tang CF; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China., Li F; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China.; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China., Ma LH; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China., Wang QN; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China., Xie PF; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China.; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China., Xiang L; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China., Zhu YJ; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China., Wang YY; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China., Zhang YZ; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China., Shi JJ; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China., Li SJ; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China., Li JM; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
Source: Frontiers in nutrition [Front Nutr] 2025 Oct 20; Vol. 12, pp. 1652968. Date of Electronic Publication: 2025 Oct 20 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 101642264 Publication Model: eCollection Cited Medium: Print ISSN: 2296-861X (Print) Linking ISSN: 2296861X NLM ISO Abbreviation: Front Nutr Subsets: PubMed not MEDLINE
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  Data: Danggui Shaoyao San attenuates depressive-like behaviors in mice via TLR4/NF-κB p65/JAK-STAT3/AKT-GSK3β signaling pathways: modulation of hippocampal neurogenesis and neuroinflammation.
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  Data: <searchLink fieldCode="AU" term="%22Tang+CF%22">Tang CF</searchLink>; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China.; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Ma+LH%22">Ma LH</searchLink>; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Wang+QN%22">Wang QN</searchLink>; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Xie+PF%22">Xie PF</searchLink>; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China.; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Xiang+L%22">Xiang L</searchLink>; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+YJ%22">Zhu YJ</searchLink>; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Wang+YY%22">Wang YY</searchLink>; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YZ%22">Zhang YZ</searchLink>; State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture, Department of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Shi+JJ%22">Shi JJ</searchLink>; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Li+SJ%22">Li SJ</searchLink>; School of Food Science, Nanjing Xiaozhuang University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Li+JM%22">Li JM</searchLink>; School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing, China.
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  Data: <searchLink fieldCode="JN" term="%22101642264%22">Frontiers in nutrition</searchLink> [Front Nutr] 2025 Oct 20; Vol. 12, pp. 1652968. <i>Date of Electronic Publication: </i>2025 Oct 20 (<i>Print Publication: </i>2025).
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