Bone morphogenetic protein-2-independent bone formation by human iPSC-derived megakaryocytes and platelets.

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Title: Bone morphogenetic protein-2-independent bone formation by human iPSC-derived megakaryocytes and platelets.
Authors: Mizuki N; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan., Mukai M; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan. Electronic address: mmukai@chiba-u.jp., Shiga Y; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan. Electronic address: yshiga1111@yahoo.co.jp., Takayama N; Department of Regenerative Medicine, Chiba University Graduate School of Medicine, Chiba, Japan., Nakamura S; Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan., Kosaka K; Department of Plastic, Reconstructive, and Aesthetic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan., Chen SJ; Department of Regenerative Medicine, Chiba University Graduate School of Medicine, Chiba, Japan., Paul SK; Department of Regenerative Medicine, Chiba University Graduate School of Medicine, Chiba, Japan., Arai T; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan., Tashiro S; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan., Sato M; Department of Orthopedic Surgery, Eastern Chiba Medical Center, Chiba, Japan., Fukuyo M; Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan., Rahmutulla B; Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan., Tajiri I; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan., Inage K; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan., Suzuki-Narita M; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan; Department of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan., Eguchi Y; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan., Orita S; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan; Center for Frontier Medical Engineering, Chiba University, Chiba, Japan., Kaneda A; Department of Molecular Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan; Health and Disease Omics Center, Chiba University, Chiba, Japan., Eto K; Department of Regenerative Medicine, Chiba University Graduate School of Medicine, Chiba, Japan; Department of Clinical Application, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan. Electronic address: eto.koji.8a@kyoto-u.ac.jp., Ohtori S; Department of Orthopedic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
Source: Bone [Bone] 2026 Feb; Vol. 203, pp. 117703. Date of Electronic Publication: 2025 Nov 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2763
DOI:10.1016/j.bone.2025.117703