Aerobic exercise improves the high-fat diet/streptozotocin-induced depression-like behaviors by reducing hippocampal neuroinflammation through suppressing the BTK/NF-κB signaling pathway.
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| Title: | Aerobic exercise improves the high-fat diet/streptozotocin-induced depression-like behaviors by reducing hippocampal neuroinflammation through suppressing the BTK/NF-κB signaling pathway. |
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| Authors: | Zhang XY; School of Kinesiology, Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, The Key Laboratory of Exercise and Health Sciences of Ministry of Education Shanghai University of Sport, Shanghai 200438, China; Department of Physiology, Naval Medical University, Shanghai 200433, China., Xu DH; School of Kinesiology, Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, The Key Laboratory of Exercise and Health Sciences of Ministry of Education Shanghai University of Sport, Shanghai 200438, China; Department of Physiology, Naval Medical University, Shanghai 200433, China., Huang JQ; Department of Physiology, Naval Medical University, Shanghai 200433, China., Zhan JH; School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China., Han F; School of Kinesiology, Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, The Key Laboratory of Exercise and Health Sciences of Ministry of Education Shanghai University of Sport, Shanghai 200438, China., Du JK; Department of Physiology, Naval Medical University, Shanghai 200433, China., Liu J; School of Kinesiology, Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, The Key Laboratory of Exercise and Health Sciences of Ministry of Education Shanghai University of Sport, Shanghai 200438, China., Li ZB; Department of Cardiology, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, China. Electronic address: lizongbin@301hospital.com.cn., Zhu XY; Department of Physiology, Naval Medical University, Shanghai 200433, China. Electronic address: xiaoyanzhu@smmu.edu.cn., Liu YJ; School of Kinesiology, Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, The Key Laboratory of Exercise and Health Sciences of Ministry of Education Shanghai University of Sport, Shanghai 200438, China. Electronic address: liuyujian@sus.edu.cn. |
| Source: | International immunopharmacology [Int Immunopharmacol] 2026 Jan 01; Vol. 168 (Pt 1), pp. 115756. Date of Electronic Publication: 2025 Nov 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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