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Molecular basis for selection and inhibition of HIV-1 escape virus by T cells and KIR2DL2+NK cells.

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Title: Molecular basis for selection and inhibition of HIV-1 escape virus by T cells and KIR2DL2+NK cells.
Authors: Chikata T; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan., Kuroki K; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Kuse N; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan., Kliszczak AE; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Paes W; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Tomioka N; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Parker R; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Aflalo A; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Akahoshi T; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan., Zhang Y; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan., Yamashita R; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Sakata R; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Kusaka H; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Watanabe Y; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Nicastri A; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Matsubara H; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Ose T; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Kita S; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Oka S; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan., Gatanaga H; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan., Lin Z; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan., Ternette N; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Borrow P; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. persephone.borrow@ndm.ox.ac.uk., Maenaka K; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Global Station for Biosurfaces and Drug Discovery, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. maenaka@pharm.hokudai.ac.jp., Takiguchi M; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan. masafumi@kumamoto-u.ac.jp.
Source: Nature communications [Nat Commun] 2025 Nov 06; Vol. 16 (1), pp. 9796. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Molecular basis for selection and inhibition of HIV-1 escape virus by T cells and KIR2DL2<superscript>+</superscript>NK cells.
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  Data: <searchLink fieldCode="AU" term="%22Chikata+T%22">Chikata T</searchLink>; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kuroki+K%22">Kuroki K</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Kuse+N%22">Kuse N</searchLink>; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kliszczak+AE%22">Kliszczak AE</searchLink>; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Paes+W%22">Paes W</searchLink>; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Tomioka+N%22">Tomioka N</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Parker+R%22">Parker R</searchLink>; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Aflalo+A%22">Aflalo A</searchLink>; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Akahoshi+T%22">Akahoshi T</searchLink>; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamashita+R%22">Yamashita R</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Sakata+R%22">Sakata R</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Kusaka+H%22">Kusaka H</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+Y%22">Watanabe Y</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Nicastri+A%22">Nicastri A</searchLink>; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Matsubara+H%22">Matsubara H</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Ose+T%22">Ose T</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Kita+S%22">Kita S</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Oka+S%22">Oka S</searchLink>; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Gatanaga+H%22">Gatanaga H</searchLink>; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ternette+N%22">Ternette N</searchLink>; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Borrow+P%22">Borrow P</searchLink>; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. persephone.borrow@ndm.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Maenaka+K%22">Maenaka K</searchLink>; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Global Station for Biosurfaces and Drug Discovery, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.; Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. maenaka@pharm.hokudai.ac.jp.<br /><searchLink fieldCode="AU" term="%22Takiguchi+M%22">Takiguchi M</searchLink>; Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan. masafumi@kumamoto-u.ac.jp.
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