Single-cell profiling unveils the immuno-favorable tumor microenvironment remodeling after successful neoadjuvant therapy for advanced gallbladder cancer.
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| Title: | Single-cell profiling unveils the immuno-favorable tumor microenvironment remodeling after successful neoadjuvant therapy for advanced gallbladder cancer. |
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| Authors: | Tang QY; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang YJ; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wu ZY; Department of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Zhang TY; Shanghai Institute of Immunology & Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Song XL; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhu YD; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Yang ZY; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao C; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhao JW; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wang HK; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Yang Y; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang Y; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Dai WT; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Jiang L; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhai YY; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Huang CX; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Immunology & Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Wu XS; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China., Gong W; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China. |
| Source: | International journal of surgery (London, England) [Int J Surg] 2026 Feb 01; Vol. 112 (2), pp. 4110-4124. Date of Electronic Publication: 2025 Nov 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101228232 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1743-9159 (Electronic) Linking ISSN: 17439159 NLM ISO Abbreviation: Int J Surg Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41202319 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Single-cell profiling unveils the immuno-favorable tumor microenvironment remodeling after successful neoadjuvant therapy for advanced gallbladder cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tang+QY%22">Tang QY</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YJ%22">Zhang YJ</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+ZY%22">Wu ZY</searchLink>; Department of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+TY%22">Zhang TY</searchLink>; Shanghai Institute of Immunology & Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Song+XL%22">Song XL</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhu+YD%22">Zhu YD</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+ZY%22">Yang ZY</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+C%22">Zhao C</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+JW%22">Zhao JW</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wang+HK%22">Wang HK</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Dai+WT%22">Dai WT</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhai+YY%22">Zhai YY</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Huang+CX%22">Huang CX</searchLink>; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Immunology & Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Wu+XS%22">Wu XS</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Gong+W%22">Gong W</searchLink>; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai, China.; Biliary Disease Research Institute of Shanghai Jiao Tong University School of Medicine, Shanghai, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101228232%22">International journal of surgery (London, England)</searchLink> [Int J Surg] 2026 Feb 01; Vol. 112 (2), pp. 4110-4124. <i>Date of Electronic Publication: </i>2025 Nov 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+Inc%22">Wolters Kluwer Health, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101228232 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1743-9159 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217439159%22">17439159 </searchLink><i>NLM ISO Abbreviation: </i>Int J Surg <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1097/JS9.0000000000003883 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 4110 Titles: – TitleFull: Single-cell profiling unveils the immuno-favorable tumor microenvironment remodeling after successful neoadjuvant therapy for advanced gallbladder cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tang QY – PersonEntity: Name: NameFull: Zhang YJ – PersonEntity: Name: NameFull: Wu ZY – PersonEntity: Name: NameFull: Zhang TY – PersonEntity: Name: NameFull: Song XL – PersonEntity: Name: NameFull: Zhu YD – PersonEntity: Name: NameFull: Yang ZY – PersonEntity: Name: NameFull: Zhao C – PersonEntity: Name: NameFull: Zhao JW – PersonEntity: Name: NameFull: Wang HK – PersonEntity: Name: NameFull: Yang Y – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Dai WT – PersonEntity: Name: NameFull: Jiang L – PersonEntity: Name: NameFull: Zhai YY – PersonEntity: Name: NameFull: Huang CX – PersonEntity: Name: NameFull: Wu XS – PersonEntity: Name: NameFull: Gong W IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2026 Feb 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1743-9159 Numbering: – Type: volume Value: 112 – Type: issue Value: 2 Titles: – TitleFull: International journal of surgery (London, England) Type: main |
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