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Chromosome 15q15 Deletion Drives Brain Metastasis in NSCLC.

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Title: Chromosome 15q15 Deletion Drives Brain Metastasis in NSCLC.
Authors: Miyakoshi J; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Shiraishi K; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Clinical Genomics, National Cancer Center Research Institute, Tokyo, Japan., Mochizuki A; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan., Tateishi A; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Shimoda-Igawa Y; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Torasawa M; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Ono H; Department of Clinical Genomics, National Cancer Center Research Institute, Tokyo, Japan., Ohno M; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan., Yoshida Y; Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan., Yoshida T; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Kaneko S; Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan; AI Medical Engineering Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan., Yagishita S; Division of Molecular Pharmacology, National Cancer Center Research Institute, Tokyo, Japan., Hamada A; Division of Molecular Pharmacology, National Cancer Center Research Institute, Tokyo, Japan., Yatabe Y; Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan., Goto Y; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan., Suzuki T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan., Narita Y; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan., Watanabe SI; Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan., Hamamoto R; Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan; AI Medical Engineering Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan., Kohno T; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan. Electronic address: tkkohno@ncc.go.jp.
Source: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2026 Apr; Vol. 21 (4), pp. 103511. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101274235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-1380 (Electronic) Linking ISSN: 15560864 NLM ISO Abbreviation: J Thorac Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Chromosome 15q15 Deletion Drives Brain Metastasis in NSCLC.
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  Data: <searchLink fieldCode="AU" term="%22Miyakoshi+J%22">Miyakoshi J</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shiraishi+K%22">Shiraishi K</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Clinical Genomics, National Cancer Center Research Institute, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Mochizuki+A%22">Mochizuki A</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Tateishi+A%22">Tateishi A</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Shimoda-Igawa+Y%22">Shimoda-Igawa Y</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Torasawa+M%22">Torasawa M</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ono+H%22">Ono H</searchLink>; Department of Clinical Genomics, National Cancer Center Research Institute, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ohno+M%22">Ohno M</searchLink>; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+Y%22">Yoshida Y</searchLink>; Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+T%22">Yoshida T</searchLink>; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kaneko+S%22">Kaneko S</searchLink>; Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan; AI Medical Engineering Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yagishita+S%22">Yagishita S</searchLink>; Division of Molecular Pharmacology, National Cancer Center Research Institute, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hamada+A%22">Hamada A</searchLink>; Division of Molecular Pharmacology, National Cancer Center Research Institute, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yatabe+Y%22">Yatabe Y</searchLink>; Department of Diagnostic Pathology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Goto+Y%22">Goto Y</searchLink>; Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+T%22">Suzuki T</searchLink>; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.<br /><searchLink fieldCode="AU" term="%22Narita+Y%22">Narita Y</searchLink>; Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Watanabe+SI%22">Watanabe SI</searchLink>; Department of Thoracic Surgery, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Hamamoto+R%22">Hamamoto R</searchLink>; Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan; AI Medical Engineering Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kohno+T%22">Kohno T</searchLink>; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan. Electronic address: tkkohno@ncc.go.jp.
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  Data: <searchLink fieldCode="JN" term="%22101274235%22">Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer</searchLink> [J Thorac Oncol] 2026 Apr; Vol. 21 (4), pp. 103511. <i>Date of Electronic Publication: </i>2025 Nov 07.
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        Value: 10.1016/j.jtho.2025.11.001
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