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ZO-1/Tjp1 and ZO-2/Tjp2 deletion in retinal pigment epithelium causes progressive retinal degeneration.

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Title: ZO-1/Tjp1 and ZO-2/Tjp2 deletion in retinal pigment epithelium causes progressive retinal degeneration.
Authors: Ali SM; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore., Parikh BH; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore., Tan QSW; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore., Hübner B; School of Biological Sciences, Nanyang Technological University (NTU), Singapore 637551, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University (NTU), Singapore 636921, Singapore., Kozyrina AN; Interdisciplinary Centre for Clinical Research, RWTH Aachen University, 52074 Aachen, Germany.; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, 52074 Aachen, Germany., Banerjee A; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore., Zhao J; Division of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University (NTU), Singapore 637371, Singapore.; Science, Mathematics and Technology, Singapore University of Technology and Design (SUTD), Singapore 487372, Singapore., Goh D; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore., Bogireddi H; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore., Yeo SW; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore., Wong DSL; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore., Xu J; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore., Tran KC; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore., Liu Z; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore.; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore., Le YZ; Department of Medicine, Cell Biology, and Ophthalmology and Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City OK 73104, USA., Barathi VA; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore.; Academic Clinical Program, Duke-NUS Medical School, National University of Singapore, Singapore 169857, Singapore., Cheong KH; Division of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University (NTU), Singapore 637371, Singapore.; College of Computing and Data Science, Nanyang Technological University (NTU), Singapore 639798, Singapore., Di Russo J; Interdisciplinary Centre for Clinical Research, RWTH Aachen University, 52074 Aachen, Germany.; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, 52074 Aachen, Germany.; DWI - Leibniz-Institute for Interactive Materials, 52074 Aachen, Germany., Ludwig A; School of Biological Sciences, Nanyang Technological University (NTU), Singapore 637551, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University (NTU), Singapore 636921, Singapore., Hunziker W; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 117593, Singapore., Su X; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore.; Department of Ophthalmology, National University Hospital (NUH), Singapore 119228, Singapore.; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.
Source: IScience [iScience] 2025 Oct 03; Vol. 28 (11), pp. 113673. Date of Electronic Publication: 2025 Oct 03 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: ZO-1/Tjp1 and ZO-2/Tjp2 deletion in retinal pigment epithelium causes progressive retinal degeneration.
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  Data: <searchLink fieldCode="AU" term="%22Ali+SM%22">Ali SM</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Parikh+BH%22">Parikh BH</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+QSW%22">Tan QSW</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Hübner+B%22">Hübner B</searchLink>; School of Biological Sciences, Nanyang Technological University (NTU), Singapore 637551, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University (NTU), Singapore 636921, Singapore.<br /><searchLink fieldCode="AU" term="%22Kozyrina+AN%22">Kozyrina AN</searchLink>; Interdisciplinary Centre for Clinical Research, RWTH Aachen University, 52074 Aachen, Germany.; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, 52074 Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Banerjee+A%22">Banerjee A</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Division of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University (NTU), Singapore 637371, Singapore.; Science, Mathematics and Technology, Singapore University of Technology and Design (SUTD), Singapore 487372, Singapore.<br /><searchLink fieldCode="AU" term="%22Goh+D%22">Goh D</searchLink>; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Bogireddi+H%22">Bogireddi H</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Yeo+SW%22">Yeo SW</searchLink>; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore.<br /><searchLink fieldCode="AU" term="%22Wong+DSL%22">Wong DSL</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.<br /><searchLink fieldCode="AU" term="%22Tran+KC%22">Tran KC</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore.; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Le+YZ%22">Le YZ</searchLink>; Department of Medicine, Cell Biology, and Ophthalmology and Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City OK 73104, USA.<br /><searchLink fieldCode="AU" term="%22Barathi+VA%22">Barathi VA</searchLink>; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore.; Academic Clinical Program, Duke-NUS Medical School, National University of Singapore, Singapore 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheong+KH%22">Cheong KH</searchLink>; Division of Mathematical Sciences, School of Physical and Mathematical Sciences, Nanyang Technological University (NTU), Singapore 637371, Singapore.; College of Computing and Data Science, Nanyang Technological University (NTU), Singapore 639798, Singapore.<br /><searchLink fieldCode="AU" term="%22Di+Russo+J%22">Di Russo J</searchLink>; Interdisciplinary Centre for Clinical Research, RWTH Aachen University, 52074 Aachen, Germany.; Institute of Molecular and Cellular Anatomy, RWTH Aachen University, 52074 Aachen, Germany.; DWI - Leibniz-Institute for Interactive Materials, 52074 Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Ludwig+A%22">Ludwig A</searchLink>; School of Biological Sciences, Nanyang Technological University (NTU), Singapore 637551, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University (NTU), Singapore 636921, Singapore.<br /><searchLink fieldCode="AU" term="%22Hunziker+W%22">Hunziker W</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 117593, Singapore.<br /><searchLink fieldCode="AU" term="%22Su+X%22">Su X</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A∗STAR), Singapore 138673, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.; Singapore Eye Research Institute (SERI), Singapore 169856, Singapore.; Department of Ophthalmology, National University Hospital (NUH), Singapore 119228, Singapore.; Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore.
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  Data: <searchLink fieldCode="JN" term="%22101724038%22">IScience</searchLink> [iScience] 2025 Oct 03; Vol. 28 (11), pp. 113673. <i>Date of Electronic Publication: </i>2025 Oct 03 (<i>Print Publication: </i>2025).
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