A multicenter dose-defining/expansion phase 1b study of first-line regorafenib plus pembrolizumab in patients with advanced hepatocellular carcinoma.
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| Title: | A multicenter dose-defining/expansion phase 1b study of first-line regorafenib plus pembrolizumab in patients with advanced hepatocellular carcinoma. |
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| Authors: | El-Khoueiry AB; Division of Medical Oncology/Hematology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA., Kim RD; Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center, Tampa, Florida, USA., Harris WP; Department of Medicine, University of Washington/Fred Hutchinson Cancer Center (FHCC), Seattle, Washington, USA., Sung MW; Division of Hematology and Oncology, Tisch Cancer Institute at Mount Sinai, New York, New York, USA., Waldschmidt D; Department of Gastroenterology and Hepatology, University Hospital Cologne, Cologne, Germany., Cabrera R; Division of Gastroenterology, Hepatology, and Nutrition, University of Florida, Gainesville, Florida, USA., Garosi VL; Bayer S.p.A., Milan, Italy., Ploeger BA; Bayer AG, Berlin, Germany., Zebger-Gong H; Bayer AG, Berlin, Germany., Brennan BJ; Bayer HealthCare Pharmaceuticals, Whippany, New Jersey, USA., Wang YA; Bayer HealthCare Pharmaceuticals, Cambridge, Massachusetts, USA., Mueller U; ClinStat GmbH, Huerth, Germany., Weispfenning A; Bayer AG, Berlin, Germany., Seidel H; Bayer AG, Berlin, Germany., Coppieters S; Bayer AG, Diegem, Belgium., Ishida TC; Bayer HealthCare Pharmaceuticals, Whippany, New Jersey, USA., Galle PR; Department of Internal Medicine, Mainz University Medical Center, Mainz, Germany. |
| Source: | Hepatology (Baltimore, Md.) [Hepatology] 2026 Jun 01; Vol. 83 (6), pp. 1433-1445. Date of Electronic Publication: 2025 Nov 10. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Multicenter Study |
| Journal Info: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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