Diversity, equity and inclusion in One Health could crucially support functional health security by fostering prevention, but a change in mindset is needed. - Robbiati C; Andriamandroso AM; Auerswald H; González MB; Becerra NC; Dente MG; Dien NT; Garnier J; Onyango D; Riley T; Weiszhar KL; Winkler AS; et al. (One health outlook, 2025)