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Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties.

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Title: Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties.
Authors: Mu M; School of Bioengineering, Zunyi Medical University, Zhuhai, China., Zhang Y; School of Bioengineering, Zunyi Medical University, Zhuhai, China., Wang B; School of Bioengineering, Zunyi Medical University, Zhuhai, China., Hu Y; School of Bioengineering, Zunyi Medical University, Zhuhai, China.
Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2025 Dec; Vol. 40 (1), pp. 2582034. Date of Electronic Publication: 2025 Nov 12.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties.
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  Data: <searchLink fieldCode="AU" term="%22Mu+M%22">Mu M</searchLink>; School of Bioengineering, Zunyi Medical University, Zhuhai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; School of Bioengineering, Zunyi Medical University, Zhuhai, China.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; School of Bioengineering, Zunyi Medical University, Zhuhai, China.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; School of Bioengineering, Zunyi Medical University, Zhuhai, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101150203 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1475-6374 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214756366%22">14756366 </searchLink><i>NLM ISO Abbreviation: </i>J Enzyme Inhib Med Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1080/14756366.2025.2582034
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      – Code: eng
        Text: English
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        StartPage: 2582034
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      – TitleFull: Design, synthesis, and evaluation of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties.
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            NameFull: Zhang Y
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            – D: 01
              M: 12
              Text: 2025 Dec
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              Y: 2025
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