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Noninvasive Therapeutic Monitoring of Circulating Tumor DNA in BRAF-Mutant Metastatic Colon Cancer Using Droplet Digital PCR, Next-Generation Sequencing, and Fragmentomics.

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Title: Noninvasive Therapeutic Monitoring of Circulating Tumor DNA in BRAF-Mutant Metastatic Colon Cancer Using Droplet Digital PCR, Next-Generation Sequencing, and Fragmentomics.
Authors: Lam RCT; Faculty of Medicine, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong., Hui CWC; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Cancer Drug Testing Unit, Hong Kong Cancer Institute, Shatin, Hong Kong., Tse IOL; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong., Zhou Q; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; Centre for Novostics, Hong Kong Science Park, Ma Liu Shui, Hong Kong.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong., Chow C; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong., Kang W; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong., Chan KCA; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; Centre for Novostics, Hong Kong Science Park, Ma Liu Shui, Hong Kong.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong., Ma BBY; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Cancer Drug Testing Unit, Hong Kong Cancer Institute, Shatin, Hong Kong.; Department of Clinical Oncology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong., Lam WKJ; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; Centre for Novostics, Hong Kong Science Park, Ma Liu Shui, Hong Kong.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.
Source: Case reports in oncological medicine [Case Rep Oncol Med] 2025 Nov 07; Vol. 2025, pp. 8140524. Date of Electronic Publication: 2025 Nov 07 (Print Publication: 2025).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101581035 Publication Model: eCollection Cited Medium: Print ISSN: 2090-6706 (Print) NLM ISO Abbreviation: Case Rep Oncol Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Noninvasive Therapeutic Monitoring of Circulating Tumor DNA in BRAF-Mutant Metastatic Colon Cancer Using Droplet Digital PCR, Next-Generation Sequencing, and Fragmentomics.
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  Data: <searchLink fieldCode="AU" term="%22Lam+RCT%22">Lam RCT</searchLink>; Faculty of Medicine, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Hui+CWC%22">Hui CWC</searchLink>; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Cancer Drug Testing Unit, Hong Kong Cancer Institute, Shatin, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Tse+IOL%22">Tse IOL</searchLink>; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; Centre for Novostics, Hong Kong Science Park, Ma Liu Shui, Hong Kong.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Chow+C%22">Chow C</searchLink>; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Kang+W%22">Kang W</searchLink>; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Chan+KCA%22">Chan KCA</searchLink>; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; Centre for Novostics, Hong Kong Science Park, Ma Liu Shui, Hong Kong.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Ma+BBY%22">Ma BBY</searchLink>; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Cancer Drug Testing Unit, Hong Kong Cancer Institute, Shatin, Hong Kong.; Department of Clinical Oncology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.<br /><searchLink fieldCode="AU" term="%22Lam+WKJ%22">Lam WKJ</searchLink>; State Key Laboratory of Translational Oncology, Sir YK Pao Centre for Cancer, Shatin, Hong Kong.; Department of Chemical Pathology, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.; Centre for Novostics, Hong Kong Science Park, Ma Liu Shui, Hong Kong.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Ma Liu Shui, Hong Kong.
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  Data: <searchLink fieldCode="JN" term="%22101581035%22">Case reports in oncological medicine</searchLink> [Case Rep Oncol Med] 2025 Nov 07; Vol. 2025, pp. 8140524. <i>Date of Electronic Publication: </i>2025 Nov 07 (<i>Print Publication: </i>2025).
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              Text: 2025 Nov 07
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