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Diagnostic Yield of Next-Generation Sequencing in CSF or Brain Biopsy for Severe Encephalitis Requiring Intensive Care.

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Title: Diagnostic Yield of Next-Generation Sequencing in CSF or Brain Biopsy for Severe Encephalitis Requiring Intensive Care.
Authors: Benghanem S; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France., Pérot P; Institut Pasteur, Université Paris Cité, Paris, France., Rodriguez C; Virology Department, Henri Mondor Hospital, APHP, Paris, France., Fourgeaud J; Microbiology Department, APHP, Centre, Hôpital Necker, Paris, France., Bouguerra M; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France., Mathon B; Neurosurgery Department, Pitié Salpêtrière Hospital, APHP, Paris, France; and., Seilhean DD; Neuropathology Department, Pitié Salpêtrière Hospital, APHP, Paris, France., Bielle F; Neuropathology Department, Pitié Salpêtrière Hospital, APHP, Paris, France., Plu I; Neuropathology Department, Pitié Salpêtrière Hospital, APHP, Paris, France., Jamet A; Microbiology Department, APHP, Centre, Hôpital Necker, Paris, France., Weiss N; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France., Marois C; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France., Rohaut B; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France., Eloit M; Institut Pasteur, Université Paris Cité, Paris, France., Demeret S; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France.
Source: Neurology. Clinical practice [Neurol Clin Pract] 2025 Dec; Vol. 15 (6), pp. e200558. Date of Electronic Publication: 2025 Nov 12.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101577149 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2163-0402 (Print) Linking ISSN: 21630402 NLM ISO Abbreviation: Neurol Clin Pract Subsets: PubMed not MEDLINE
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  Data: Diagnostic Yield of Next-Generation Sequencing in CSF or Brain Biopsy for Severe Encephalitis Requiring Intensive Care.
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  Data: <searchLink fieldCode="AU" term="%22Benghanem+S%22">Benghanem S</searchLink>; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Pérot+P%22">Pérot P</searchLink>; Institut Pasteur, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rodriguez+C%22">Rodriguez C</searchLink>; Virology Department, Henri Mondor Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Fourgeaud+J%22">Fourgeaud J</searchLink>; Microbiology Department, APHP, Centre, Hôpital Necker, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bouguerra+M%22">Bouguerra M</searchLink>; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mathon+B%22">Mathon B</searchLink>; Neurosurgery Department, Pitié Salpêtrière Hospital, APHP, Paris, France; and.<br /><searchLink fieldCode="AU" term="%22Seilhean+DD%22">Seilhean DD</searchLink>; Neuropathology Department, Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bielle+F%22">Bielle F</searchLink>; Neuropathology Department, Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Plu+I%22">Plu I</searchLink>; Neuropathology Department, Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Jamet+A%22">Jamet A</searchLink>; Microbiology Department, APHP, Centre, Hôpital Necker, Paris, France.<br /><searchLink fieldCode="AU" term="%22Weiss+N%22">Weiss N</searchLink>; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Marois+C%22">Marois C</searchLink>; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rohaut+B%22">Rohaut B</searchLink>; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Eloit+M%22">Eloit M</searchLink>; Institut Pasteur, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Demeret+S%22">Demeret S</searchLink>; Neuro-intensive Care Unit, Sorbonne University, APHP, Sorbonne Université, La Pitié Salpêtrière Hospital, APHP, Paris, France.
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              Text: 2025 Dec
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