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Characterizing and controlling CRISPR repair outcomes in nondividing human cells.

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Title: Characterizing and controlling CRISPR repair outcomes in nondividing human cells.
Authors: Ramadoss GN; Gladstone Institutes, San Francisco, CA, USA.; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA, USA., Namaganda SJ; Gladstone Institutes, San Francisco, CA, USA., Kumar MM; Gladstone Institutes, San Francisco, CA, USA., Hamilton JR; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Molecular & Cell Biology, University of California, Berkeley, CA, USA., Sharma R; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Bioengineering, University of California, Berkeley, CA, USA., Chow KG; Gladstone Institutes, San Francisco, CA, USA., Workley LA; Gladstone Institutes, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Macklin BL; Gladstone Institutes, San Francisco, CA, USA., Sun M; Gladstone Institutes, San Francisco, CA, USA., Ha AS; Gladstone Institutes, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Liu JC; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Fellmann C; Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular & Molecular Pharmacology, University of California, San Francisco, CA, USA., Watry HL; Gladstone Institutes, San Francisco, CA, USA., Dierks PH; Gladstone Institutes, San Francisco, CA, USA., Bose RS; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA, USA., Jin J; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA, USA., Perez BS; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Molecular & Cell Biology, University of California, Berkeley, CA, USA., Sandoval Espinoza CR; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Molecular & Cell Biology, University of California, Berkeley, CA, USA., Matia MP; Gladstone Institutes, San Francisco, CA, USA., Lu SH; Gladstone Institutes, San Francisco, CA, USA., Judge LM; Gladstone Institutes, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, CA, USA., Shy BR; Gladstone Institutes, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA., Nussenzweig A; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA., Adamson B; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA., Murthy N; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Bioengineering, University of California, Berkeley, CA, USA., Doudna JA; Gladstone Institutes, San Francisco, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Molecular & Cell Biology, University of California, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA, USA.; Department of Chemistry, University of California, Berkeley, CA, USA.; MBIB Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Kampmann M; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA, USA.; Department of Biochemistry & Biophysics, University of California, San Francisco, CA, USA., Conklin BR; Gladstone Institutes, San Francisco, CA, USA. bconklin@gladstone.ucsf.edu.; Innovative Genomics Institute, University of California, Berkeley, CA, USA. bconklin@gladstone.ucsf.edu.; Department of Cellular & Molecular Pharmacology, University of California, San Francisco, CA, USA. bconklin@gladstone.ucsf.edu.; Department of Medicine, University of California, San Francisco, CA, USA. bconklin@gladstone.ucsf.edu.
Source: Nature communications [Nat Commun] 2025 Nov 17; Vol. 16 (1), pp. 9883. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Workley+LA%22">Workley LA</searchLink>; Gladstone Institutes, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Macklin+BL%22">Macklin BL</searchLink>; Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sun+M%22">Sun M</searchLink>; Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ha+AS%22">Ha AS</searchLink>; Gladstone Institutes, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+JC%22">Liu JC</searchLink>; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Fellmann+C%22">Fellmann C</searchLink>; Gladstone Institutes, San Francisco, CA, USA.; Department of Cellular & Molecular Pharmacology, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Watry+HL%22">Watry HL</searchLink>; 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Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+SH%22">Lu SH</searchLink>; Gladstone Institutes, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Judge+LM%22">Judge LM</searchLink>; Gladstone Institutes, San Francisco, CA, USA.; Department of Pediatrics, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shy+BR%22">Shy BR</searchLink>; Gladstone Institutes, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nussenzweig+A%22">Nussenzweig A</searchLink>; Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Adamson+B%22">Adamson B</searchLink>; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Murthy+N%22">Murthy N</searchLink>; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Bioengineering, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Doudna+JA%22">Doudna JA</searchLink>; Gladstone Institutes, San Francisco, CA, USA.; Innovative Genomics Institute, University of California, Berkeley, CA, USA.; Department of Molecular & Cell Biology, University of California, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, CA, USA.; Howard Hughes Medical Institute, University of California, Berkeley, CA, USA.; Department of Chemistry, University of California, Berkeley, CA, USA.; MBIB Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kampmann+M%22">Kampmann M</searchLink>; Institute for Neurodegenerative Diseases, University of California, San Francisco, CA, USA.; Department of Biochemistry & Biophysics, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Conklin+BR%22">Conklin BR</searchLink>; Gladstone Institutes, San Francisco, CA, USA. bconklin@gladstone.ucsf.edu.; Innovative Genomics Institute, University of California, Berkeley, CA, USA. bconklin@gladstone.ucsf.edu.; Department of Cellular & Molecular Pharmacology, University of California, San Francisco, CA, USA. bconklin@gladstone.ucsf.edu.; Department of Medicine, University of California, San Francisco, CA, USA. bconklin@gladstone.ucsf.edu.
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