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Therapeutic impact of leuprorelin acetate on spinal and bulbar muscular atrophy: pre- and post-marketing observational study.

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Title: Therapeutic impact of leuprorelin acetate on spinal and bulbar muscular atrophy: pre- and post-marketing observational study.
Authors: Hashizume A; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. hashizume.atsushi.x1@f.mail.nagoya-u.ac.jp.; Department of Clinical Research Education, Nagoya University Graduate School of Medicine, Tsurumaicho, Showa-ku, Nagoya, 466-8550, Japan. hashizume.atsushi.x1@f.mail.nagoya-u.ac.jp.; Department of Advanced Medicine, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8650, Japan. hashizume.atsushi.x1@f.mail.nagoya-u.ac.jp., Hanazawa R; Department of Clinical Biostatistics, Graduate School of Medical and Dental Science, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo ku, Tokyo, 113-8510, Japan., Yamada S; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Ito D; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Kishimoto Y; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Komori S; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Kawase T; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Iida M; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Kondo A; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Mori Y; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Obara K; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan., Morita M; Division of Neurology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan., Yamamoto T; Department of Performance Monitoring and Risk Management, The University of Tokyo Hospital, Tokyo, Japan., Sato H; Department of Clinical Biostatistics, Graduate School of Medical and Dental Science, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo ku, Tokyo, 113-8510, Japan., Hirakawa A; Department of Clinical Biostatistics, Graduate School of Medical and Dental Science, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo ku, Tokyo, 113-8510, Japan., Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. katsuno.masahisa.i1@f.mail.nagoya-u.ac.jp.
Source: Journal of neurology [J Neurol] 2025 Nov 19; Vol. 272 (12), pp. 772. Date of Electronic Publication: 2025 Nov 19.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
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  Data: Therapeutic impact of leuprorelin acetate on spinal and bulbar muscular atrophy: pre- and post-marketing observational study.
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  Data: <searchLink fieldCode="AU" term="%22Hashizume+A%22">Hashizume A</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. hashizume.atsushi.x1@f.mail.nagoya-u.ac.jp.; Department of Clinical Research Education, Nagoya University Graduate School of Medicine, Tsurumaicho, Showa-ku, Nagoya, 466-8550, Japan. hashizume.atsushi.x1@f.mail.nagoya-u.ac.jp.; Department of Advanced Medicine, Nagoya University Hospital, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8650, Japan. hashizume.atsushi.x1@f.mail.nagoya-u.ac.jp.<br /><searchLink fieldCode="AU" term="%22Hanazawa+R%22">Hanazawa R</searchLink>; Department of Clinical Biostatistics, Graduate School of Medical and Dental Science, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo ku, Tokyo, 113-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+S%22">Yamada S</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Ito+D%22">Ito D</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Kishimoto+Y%22">Kishimoto Y</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Komori+S%22">Komori S</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Kawase+T%22">Kawase T</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Iida+M%22">Iida M</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Kondo+A%22">Kondo A</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Mori+Y%22">Mori Y</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Obara+K%22">Obara K</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.<br /><searchLink fieldCode="AU" term="%22Morita+M%22">Morita M</searchLink>; Division of Neurology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+T%22">Yamamoto T</searchLink>; Department of Performance Monitoring and Risk Management, The University of Tokyo Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+H%22">Sato H</searchLink>; Department of Clinical Biostatistics, Graduate School of Medical and Dental Science, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo ku, Tokyo, 113-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Hirakawa+A%22">Hirakawa A</searchLink>; Department of Clinical Biostatistics, Graduate School of Medical and Dental Science, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo ku, Tokyo, 113-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Katsuno+M%22">Katsuno M</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. katsuno.masahisa.i1@f.mail.nagoya-u.ac.jp.
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