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Validation of the pathology-adjusted Manchester scoring system in over 10 000 assessments of cases with breast and/or ovarian cancer.

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Title: Validation of the pathology-adjusted Manchester scoring system in over 10 000 assessments of cases with breast and/or ovarian cancer.
Authors: Evans DG; Genomic Medicine, University of Manchester - The Victoria University of Manchester Campus, Manchester, UK gareth.d.evans@manchester.ac.uk.; Genomic Diagnostic Laboratory, Manchester University NHS Foundation Trust, Manchester, UK., Morgan RD; Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.; cancer studies, University of Manchester, Manchester, UK., Forde C; Clinical Genetics Service, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Crosbie EJ; Division of Molecular and Clinical Cancer Sciences, The University of Manchester, Manchester, UK.; University of Manchester, Manchester, UK., Burghel GJ; Genomic Diagnostic Laboratory, Manchester University NHS Foundation Trust, Manchester, UK., Pugh S; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK., Gandhi A; Prevent Breast Cancer Centre, Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, UK., Howell A; Prevent Breast Cancer Centre, Manchester, UK., Howell SJ; Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, UK.; The Christie NHS Foundation Trust, Manchester, UK., Woodward ER; Manchester Centre for Genomic Medicine, Central Manchester NHS Foundation Trust, Manchester, UK., Lalloo F; Clinical Genetics Service, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Source: Journal of medical genetics [J Med Genet] 2026 Jan 20; Vol. 63 (2), pp. 123-131. Date of Electronic Publication: 2026 Jan 20.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: British Medical Association Country of Publication: England NLM ID: 2985087R Publication Model: Electronic Cited Medium: Internet ISSN: 1468-6244 (Electronic) Linking ISSN: 00222593 NLM ISO Abbreviation: J Med Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Validation of the pathology-adjusted Manchester scoring system in over 10 000 assessments of cases with breast and/or ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Evans+DG%22">Evans DG</searchLink>; Genomic Medicine, University of Manchester - The Victoria University of Manchester Campus, Manchester, UK gareth.d.evans@manchester.ac.uk.; Genomic Diagnostic Laboratory, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Morgan+RD%22">Morgan RD</searchLink>; Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.; cancer studies, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Forde+C%22">Forde C</searchLink>; Clinical Genetics Service, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Crosbie+EJ%22">Crosbie EJ</searchLink>; Division of Molecular and Clinical Cancer Sciences, The University of Manchester, Manchester, UK.; University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Burghel+GJ%22">Burghel GJ</searchLink>; Genomic Diagnostic Laboratory, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Pugh+S%22">Pugh S</searchLink>; Manchester Centre for Genomic Medicine, Manchester University NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Gandhi+A%22">Gandhi A</searchLink>; Prevent Breast Cancer Centre, Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, UK.<br /><searchLink fieldCode="AU" term="%22Howell+A%22">Howell A</searchLink>; Prevent Breast Cancer Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Howell+SJ%22">Howell SJ</searchLink>; Wythenshawe Hospital Manchester Universities Foundation Trust, Wythenshawe, UK.; The Christie NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Woodward+ER%22">Woodward ER</searchLink>; Manchester Centre for Genomic Medicine, Central Manchester NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Lalloo+F%22">Lalloo F</searchLink>; Clinical Genetics Service, Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
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  Data: <searchLink fieldCode="JN" term="%222985087R%22">Journal of medical genetics</searchLink> [J Med Genet] 2026 Jan 20; Vol. 63 (2), pp. 123-131. <i>Date of Electronic Publication: </i>2026 Jan 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22British+Medical+Association%22">British Medical Association </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985087R <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1468-6244 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222593%22">00222593 </searchLink><i>NLM ISO Abbreviation: </i>J Med Genet <i>Subsets: </i>MEDLINE
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        Value: 10.1136/jmg-2025-110869
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              Text: 2026 Jan 20
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