Dual PI3K and HDAC inhibitor, CUDC-907, effectively inhibits endometrial cancer growth in vitro and in vivo.

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Title: Dual PI3K and HDAC inhibitor, CUDC-907, effectively inhibits endometrial cancer growth in vitro and in vivo.
Authors: Zhang X; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Lazaro-Camp V; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Li T; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Qi A; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Lan L; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Lamont L; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Zhao L; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Meehan MR; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Gardner SN; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Meng W; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Xiong Y; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Leidinger M; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Department of Ophthalmology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Imai Y; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, United States., Meng X; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States., Yang S; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States.
Source: Frontiers in oncology [Front Oncol] 2025 Nov 04; Vol. 15, pp. 1531805. Date of Electronic Publication: 2025 Nov 04 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
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  Data: Dual PI3K and HDAC inhibitor, CUDC-907, effectively inhibits endometrial cancer growth in vitro and in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Lazaro-Camp+V%22">Lazaro-Camp V</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Qi+A%22">Qi A</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Lan+L%22">Lan L</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Lamont+L%22">Lamont L</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Meehan+MR%22">Meehan MR</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Gardner+SN%22">Gardner SN</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Meng+W%22">Meng W</searchLink>; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Xiong+Y%22">Xiong Y</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Leidinger+M%22">Leidinger M</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Department of Ophthalmology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Imai+Y%22">Imai Y</searchLink>; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Meng+X%22">Meng X</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States.; Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, United States.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101568867 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2234-943X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222234943X%22">2234943X </searchLink><i>NLM ISO Abbreviation: </i>Front Oncol <i>Subsets: </i>PubMed not MEDLINE
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