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Hypothalamic Prostaglandins Facilitate Recovery From Severe Hypoglycemia but Exacerbate Recurrent Hypoglycemia in Mice.

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Title: Hypothalamic Prostaglandins Facilitate Recovery From Severe Hypoglycemia but Exacerbate Recurrent Hypoglycemia in Mice.
Authors: Abe T; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Xu S; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan., Sugiura Y; Multiomics Platform, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Arima Y; International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan., Hayasaka T; Institute for the Advancement of Higher Education, Hokkaido University, Hokkaido, Japan., Lee ML; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences (NINS), Aichi, Japan., Ishimoto T; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Araki Y; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Ngurari S; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Niu Z; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan., Iijima N; National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan., Diano S; Institute of Human Nutrition, Columbia University Irving Medical Center, New York, NY., Toda C; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Source: Diabetes [Diabetes] 2025 Dec 01; Vol. 74 (12), pp. 2390-2404.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hypothalamic Prostaglandins Facilitate Recovery From Severe Hypoglycemia but Exacerbate Recurrent Hypoglycemia in Mice.
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  Data: <searchLink fieldCode="AU" term="%22Abe+T%22">Abe T</searchLink>; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Xu+S%22">Xu S</searchLink>; Laboratory of Biochemistry, Graduate School of Veterinary Medicine, Hokkaido University, Hokkaido, Japan.<br /><searchLink fieldCode="AU" term="%22Sugiura+Y%22">Sugiura Y</searchLink>; Multiomics Platform, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto, Japan.<br /><searchLink fieldCode="AU" term="%22Arima+Y%22">Arima Y</searchLink>; International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Hayasaka+T%22">Hayasaka T</searchLink>; Institute for the Advancement of Higher Education, Hokkaido University, Hokkaido, Japan.<br /><searchLink fieldCode="AU" term="%22Lee+ML%22">Lee ML</searchLink>; Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences (NINS), Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Ishimoto+T%22">Ishimoto T</searchLink>; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Araki+Y%22">Araki Y</searchLink>; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Ngurari+S%22">Ngurari S</searchLink>; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Niu+Z%22">Niu Z</searchLink>; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Iijima+N%22">Iijima N</searchLink>; National Institutes of Biomedical Innovation, Health and Nutrition, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Diano+S%22">Diano S</searchLink>; Institute of Human Nutrition, Columbia University Irving Medical Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Toda+C%22">Toda C</searchLink>; Department of Neuroscience for Metabolic Control, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
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  Data: <searchLink fieldCode="JN" term="%220372763%22">Diabetes</searchLink> [Diabetes] 2025 Dec 01; Vol. 74 (12), pp. 2390-2404.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372763 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1939-327X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200121797%22">00121797 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes <i>Subsets: </i>MEDLINE
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