Leveraging protein language models to identify complex trait associations with previously inaccessible classes of functional rare variants.
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| Title: | Leveraging protein language models to identify complex trait associations with previously inaccessible classes of functional rare variants. |
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| Authors: | Jang SK; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Wang Z; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Border R; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Computer Science, University of California, Los Angeles, Los Angeles, CA, USA., Tuan D; Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA, USA., Wei A; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., An U; Department of Computer Science, University of California, Los Angeles, Los Angeles, CA, USA., Sankararaman S; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Computer Science, University of California, Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Ntranos V; Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA, USA., Flint J; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: jflint@mednet.ucla.edu., Zaitlen N; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Computational Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: nzaitlen@g.ucla.edu. |
| Source: | Cell genomics [Cell Genom] 2026 Feb 11; Vol. 6 (2), pp. 101068. Date of Electronic Publication: 2025 Nov 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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