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Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis.

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Title: Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis.
Authors: Kalvala AK; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Silwal A; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Patel B; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Kasetti A; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Shetty KR; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Markiewski J; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Cho JH; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Lara G; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Daugherity E; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA., Diesler R; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Respiratory Medicine, National Reference Centre for Rare Pulmonary Diseases, Hospices civils de Lyon, Université Lyon 1, UMR754, INRAE, ERN-LUNG, Lyon, France., Pooladanda V; Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA., Rueda BR; Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA., Henske EP; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Yu JJ; Department of Internal Medicine, University of Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Markiewski M; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA. maciej.markiewski@ttuhsc.edu., Karbowniczek M; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA. magdalena.karbowniczek@ttuhsc.edu.
Source: Communications biology [Commun Biol] 2025 Nov 20; Vol. 8 (1), pp. 1623. Date of Electronic Publication: 2025 Nov 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Extracellular vesicles modulate integrin signaling and subcellular energetics to promote pulmonary lymphangioleiomyomatosis metastasis.
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  Data: <searchLink fieldCode="AU" term="%22Kalvala+AK%22">Kalvala AK</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Silwal+A%22">Silwal A</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Patel+B%22">Patel B</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kasetti+A%22">Kasetti A</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Shetty+KR%22">Shetty KR</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Markiewski+J%22">Markiewski J</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Cho+JH%22">Cho JH</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lara+G%22">Lara G</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Daugherity+E%22">Daugherity E</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA.<br /><searchLink fieldCode="AU" term="%22Diesler+R%22">Diesler R</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Respiratory Medicine, National Reference Centre for Rare Pulmonary Diseases, Hospices civils de Lyon, Université Lyon 1, UMR754, INRAE, ERN-LUNG, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Pooladanda+V%22">Pooladanda V</searchLink>; Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rueda+BR%22">Rueda BR</searchLink>; Vincent Center for Reproductive Biology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Henske+EP%22">Henske EP</searchLink>; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+JJ%22">Yu JJ</searchLink>; Department of Internal Medicine, University of Division of Pulmonary, Critical Care and Sleep Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA.<br /><searchLink fieldCode="AU" term="%22Markiewski+M%22">Markiewski M</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA. maciej.markiewski@ttuhsc.edu.<br /><searchLink fieldCode="AU" term="%22Karbowniczek+M%22">Karbowniczek M</searchLink>; Department of Immunotherapeutics & Biotechnology, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Abilene, TX, USA. magdalena.karbowniczek@ttuhsc.edu.
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        Value: 10.1038/s42003-025-09004-9
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