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Antidepressant use in older age bipolar disorder (OABD): Results from the GAGE-BD international consortium.

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Title: Antidepressant use in older age bipolar disorder (OABD): Results from the GAGE-BD international consortium.
Authors: Rigas C; Department of Psychiatry, Jewish General Hospital/Lady Davis Research Institute, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Douglas Mental Health University Institute, Montreal, Canada. Electronic address: christina.rigas@mail.mcgill.ca., Lavin P; Department of Psychiatry, Jewish General Hospital/Lady Davis Research Institute, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Douglas Mental Health University Institute, Montreal, Canada., Chen PJ; Department of Psychiatry, Geriatric Psychiatry Division, Case Western Reserve University School of Medicine, Geriatric Research, Education and Clinical Center (GRECC), VA Northeast Ohio Healthcare System, Cleveland, OH, USA., Torres-Platas SG; Department of Psychiatry, Jewish General Hospital/Lady Davis Research Institute, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Department of Psychology, Northwestern University, Evanston, IL, USA., Su CL; Department of Psychiatry, Jewish General Hospital/Lady Davis Research Institute, Montreal, Canada., Eyler LT; Department of Psychiatry, University of California San Diego, San Diego, CA, USA; Desert-Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare System, San Diego, CA, USA., Olagunju AT; Department of Psychiatry and Behavioral Neurosciences, McMaster University/St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada., Teixeira AL; Biggs Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Dols A; Department of Psychiatry, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Psychiatry, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, the Netherlands., Alda M; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Almeida OP; Institute for Health Research of the University of Notre Dame Australia & Medical School of the University of Western Australia, Australia., Altinbas K; Selçuk University Medical Faculty, Department of Psychiatry, Mazhar Osman Mood Clinic, Konya, Turkey., Balanzá-Martínez V; Teaching Unit of Psychiatry and Psychological Medicine, Department of Medicine, University of Valencia, CIBERSAM, INCLIVA, Valencia, Spain., Barbosa IG; Laboratório Interdisciplinar de Investigação Médica da Faculdade de Medicina, Universidad Federal de Minas Gerais, Belo Horizonte, Brazil., Blumberg HP; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Briggs FBS; Department of Public Health Sciences, University of Miami, Florida, USA., Calkin CV; Department of Public Health Sciences, University of Miami, Florida, USA., Forester BP; Division of Geriatric Psychiatry, McLean Hospital, Harvard Medical School, Boston, MA, USA., Forlenza OV; Laboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, HCFMUSP, Faculdade de Medicina da Universidad de São Paulo, São Paulo, Brazil., Hajek T; National Institute of Mental Health, Klecany, Czech Republic., Haarman BCM; Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Jimenez E; Bipolar and Depressive Disorders Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain., Lafer B; Department of Psychiatry, University of Sao Paulo, São Paulo, Brazil., Mulsant B; Department of Psychiatry, University of Toronto, Center for Addiction and Mental Health, Toronto, Ontario, Canada., Oluwaniyi SO; Federal Neuro-Psychiatric Hospital Yaba, Lagos, Nigeria., Patrick R; Division of Geriatric Psychiatry, McLean Hospital, Belmont, MA, USA., Radua J; Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Solna, Sweden; Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK., Sarna K; Department of Public Health Sciences, University of Miami, Florida, USA., Schouws S; Bipolar Center Wiener Neustadt, Sigmund Freud University, Medical Faculty, Wien, Austria., Simhandl C; Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, UTHealth Houston, TX, USA., Soares JC; Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Sutherland AN; Department of Psychiatry, University of California San Diego, San Diego, CA, USA; Desert-Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare System, San Diego, CA, USA., Tsai SY; Department of Psychiatry, University of Oxford, Oxford, UK., Vieta E; Department of Psychiatry, University of Toronto, Center for Addiction and Mental Health, Toronto, Ontario, Canada., Villa LM; Departments of Psychiatry and Neurology, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA., Fiorelli N; Departments of Psychiatry and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Nunes PV; Department of Psychiatry, University of Sao Paulo, São Paulo, Brazil., Yala JM; Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, OH, USA., Sajatovic M; Departments of Psychiatry and Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Rej S; Department of Psychiatry, Jewish General Hospital/Lady Davis Research Institute, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Douglas Mental Health University Institute, Montreal, Canada.
Corporate Authors: all GAGE-BD Investigators
Source: Journal of affective disorders [J Affect Disord] 2026 Feb 15; Vol. 395 (Pt B), pp. 120704. Date of Electronic Publication: 2025 Nov 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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Department of Psychiatry, Jewish General Hospital/Lady Davis Research Institute, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Eyler+LT%22">Eyler LT</searchLink>; Department of Psychiatry, University of California San Diego, San Diego, CA, USA; Desert-Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare System, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Olagunju+AT%22">Olagunju AT</searchLink>; Department of Psychiatry and Behavioral Neurosciences, McMaster University/St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Teixeira+AL%22">Teixeira AL</searchLink>; Biggs Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dols+A%22">Dols A</searchLink>; Department of Psychiatry, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Psychiatry, Amsterdam UMC, Amsterdam Neuroscience, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Alda+M%22">Alda M</searchLink>; 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Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Jimenez+E%22">Jimenez E</searchLink>; Bipolar and Depressive Disorders Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.<br /><searchLink fieldCode="AU" term="%22Lafer+B%22">Lafer B</searchLink>; Department of Psychiatry, University of Sao Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Mulsant+B%22">Mulsant B</searchLink>; Department of Psychiatry, University of Toronto, Center for Addiction and Mental Health, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Oluwaniyi+SO%22">Oluwaniyi SO</searchLink>; Federal Neuro-Psychiatric Hospital Yaba, Lagos, Nigeria.<br /><searchLink fieldCode="AU" term="%22Patrick+R%22">Patrick R</searchLink>; Division of Geriatric Psychiatry, McLean Hospital, Belmont, MA, USA.<br /><searchLink fieldCode="AU" term="%22Radua+J%22">Radua J</searchLink>; Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Solna, Sweden; Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Sarna+K%22">Sarna K</searchLink>; Department of Public Health Sciences, University of Miami, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Schouws+S%22">Schouws S</searchLink>; Bipolar Center Wiener Neustadt, Sigmund Freud University, Medical Faculty, Wien, Austria.<br /><searchLink fieldCode="AU" term="%22Simhandl+C%22">Simhandl C</searchLink>; Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, UTHealth Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Soares+JC%22">Soares JC</searchLink>; Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Sutherland+AN%22">Sutherland AN</searchLink>; Department of Psychiatry, University of California San Diego, San Diego, CA, USA; 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