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Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse Sepsis.

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Title: Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse Sepsis.
Authors: Rodhouse C; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Wang D; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Tang H; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Polcz VE; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Hernández-Ríos M; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Yu X; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Balzano-Nogueira L; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, FL, USA., Rincon JC; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Charles A; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Fujishima S; Department of Surgery, National Defense Medical College, Namiki, Tokorozawa, Japan., Vo Q; Department of Neuroscience, University of Florida College of Medicine, Gainesville, Florida, USA., Dirain ML; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Ungaro R; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Nacionales DC; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Zeumer-Spataro L; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Langhi Prata L; Center for Advanced Gerotherapeutics, Division of Endocrinology, Diabetes & Metabolism, Cedars-Sinai Medical Center; Los Angeles, CA, USA., Larson SD; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Casadesus G; Department of Pharmacy and Therapeutics, University of Florida College of Medicine, Gainesville, FL, USA., Xiao F; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Biostatistics, University of Florida Colleges of Medicine and Public Health and Health Sciences, Gainesville, FL, USA., Wallet SM; Department of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, USA., Brusko MA; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, FL, USA., Loftus TJ; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Bible L; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Mohr AM; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Chakrabarty P; Department of Neuroscience, University of Florida College of Medicine, Gainesville, Florida, USA., Kladde MP; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL, USA., Mathews CE; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Infectious Diseases and Immunology, University of Florida College of Veterinary Medicine, Gainesville, Florida, USA., Moldawer LL; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Maile R; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Cai G; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA., Efron PA; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 07. Date of Electronic Publication: 2025 Oct 07.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse Sepsis.
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Department of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Brusko+MA%22">Brusko MA</searchLink>; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine; Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Loftus+TJ%22">Loftus TJ</searchLink>; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Bible+L%22">Bible L</searchLink>; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mohr+AM%22">Mohr AM</searchLink>; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Surgery, University of Florida College of Medicine, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Chakrabarty+P%22">Chakrabarty P</searchLink>; Department of Neuroscience, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Kladde+MP%22">Kladde MP</searchLink>; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Mathews+CE%22">Mathews CE</searchLink>; Sepsis and Critical Illness Research Center, University of Florida College of Medicine, Gainesville, FL, USA.; Department of Infectious Diseases and Immunology, University of Florida College of Veterinary Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Moldawer+LL%22">Moldawer LL</searchLink>; 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