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Disruption of Cell-Type-Specific Molecular Programs of Medium Spiny Neurons in Autism.

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Title: Disruption of Cell-Type-Specific Molecular Programs of Medium Spiny Neurons in Autism.
Authors: Yuan G; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Suresh V; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Wigdor E; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK., Hao Y; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Leonard R; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Steyert M; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Griffiths M; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK., Evans C; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Rohani N; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK., Weiss J; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.; Center for Human Genetics, University of Oxford, Oxford, UK.; The Pioneer Centre for SMARTbiomed, Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Lassen FH; Center for Human Genetics, University of Oxford, Oxford, UK.; The Pioneer Centre for SMARTbiomed, Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Schafer N; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK., Dong S; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, USA.; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA., Palmer DS; The Pioneer Centre for SMARTbiomed, Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, University of Oxford, Oxford, UK., Sanders SJ; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, University of Oxford, Oxford, UK.; New York Genome Center, New York, NY, USA., Nowakowski TJ; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, University of Oxford, Oxford, UK.; Department of Anatomy, University of California San Francisco, San Francisco, CA, USA.; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Nov 07. Date of Electronic Publication: 2025 Nov 07.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Disruption of Cell-Type-Specific Molecular Programs of Medium Spiny Neurons in Autism.
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  Data: <searchLink fieldCode="AU" term="%22Yuan+G%22">Yuan G</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Suresh+V%22">Suresh V</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wigdor+E%22">Wigdor E</searchLink>; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Hao+Y%22">Hao Y</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Leonard+R%22">Leonard R</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Steyert+M%22">Steyert M</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Griffiths+M%22">Griffiths M</searchLink>; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Evans+C%22">Evans C</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rohani+N%22">Rohani N</searchLink>; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Weiss+J%22">Weiss J</searchLink>; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.; Center for Human Genetics, University of Oxford, Oxford, UK.; The Pioneer Centre for SMARTbiomed, Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lassen+FH%22">Lassen FH</searchLink>; Center for Human Genetics, University of Oxford, Oxford, UK.; The Pioneer Centre for SMARTbiomed, Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Schafer+N%22">Schafer N</searchLink>; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Dong+S%22">Dong S</searchLink>; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA, USA.; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+DS%22">Palmer DS</searchLink>; The Pioneer Centre for SMARTbiomed, Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Sanders+SJ%22">Sanders SJ</searchLink>; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, UK.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, University of Oxford, Oxford, UK.; New York Genome Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nowakowski+TJ%22">Nowakowski TJ</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, University of Oxford, Oxford, UK.; Department of Anatomy, University of California San Francisco, San Francisco, CA, USA.; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
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