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Compensatory tRNA Modification by DUS3L Confers Resistance to METTL1 Loss in Oesophageal Cancer.

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Title: Compensatory tRNA Modification by DUS3L Confers Resistance to METTL1 Loss in Oesophageal Cancer.
Authors: Santos-Rosa H; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; These authors contributed equally., Price JL; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; These authors contributed equally., Tsagkogeorga G; Milner Therapeutics Institute, University of Cambridge, Cambridge CB2 0AW, UK.; STORM Therapeutics Ltd, Babraham Research Campus, Cambridge CB22 3AT, UK.; Current address: Mosaic Therapeutics Ltd., Babraham Research Campus, Cambridge CB22 3FH, UK., Sapetschnig A; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; STORM Therapeutics Ltd, Babraham Research Campus, Cambridge CB22 3AT, UK., Pierattini B; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK., Jordan D; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK., Milan-Rois P; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK., Serrano-Benitez A; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK., Stott K; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Han N; Milner Therapeutics Institute, University of Cambridge, Cambridge CB2 0AW, UK., Kouzarides T; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; Milner Therapeutics Institute, University of Cambridge, Cambridge CB2 0AW, UK., Miska EA; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; Lead author.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 13. Date of Electronic Publication: 2025 Oct 13.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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