Compensatory tRNA Modification by DUS3L Confers Resistance to METTL1 Loss in Oesophageal Cancer.
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| Title: | Compensatory tRNA Modification by DUS3L Confers Resistance to METTL1 Loss in Oesophageal Cancer. |
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| Authors: | Santos-Rosa H; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; These authors contributed equally., Price JL; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; These authors contributed equally., Tsagkogeorga G; Milner Therapeutics Institute, University of Cambridge, Cambridge CB2 0AW, UK.; STORM Therapeutics Ltd, Babraham Research Campus, Cambridge CB22 3AT, UK.; Current address: Mosaic Therapeutics Ltd., Babraham Research Campus, Cambridge CB22 3FH, UK., Sapetschnig A; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; STORM Therapeutics Ltd, Babraham Research Campus, Cambridge CB22 3AT, UK., Pierattini B; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK., Jordan D; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK., Milan-Rois P; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK., Serrano-Benitez A; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge CB2 0RE, UK., Stott K; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK., Han N; Milner Therapeutics Institute, University of Cambridge, Cambridge CB2 0AW, UK., Kouzarides T; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; Milner Therapeutics Institute, University of Cambridge, Cambridge CB2 0AW, UK., Miska EA; Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.; Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.; Lead author. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 13. Date of Electronic Publication: 2025 Oct 13. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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