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A Compound Enhancing Lysosomal Function Reduces Tau Pathology, Microglial Reactivity and Rescues Working Memory in 3xTg AD Mice.

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Title: A Compound Enhancing Lysosomal Function Reduces Tau Pathology, Microglial Reactivity and Rescues Working Memory in 3xTg AD Mice.
Authors: Mayeri Z; Buck Institute for Research on Aging, Novato, CA, USA., Woods G; Buck Institute for Research on Aging, Novato, CA, USA., Rane A; Buck Institute for Research on Aging, Novato, CA, USA., Kifle A; Buck Institute for Research on Aging, Novato, CA, USA., Chamoli M; Buck Institute for Research on Aging, Novato, CA, USA., Shukla S; Buck Institute for Research on Aging, Novato, CA, USA., Walton CC; Buck Institute for Research on Aging, Novato, CA, USA., Andersen JK; Buck Institute for Research on Aging, Novato, CA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Nov 12. Date of Electronic Publication: 2025 Nov 12.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41292940
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: A Compound Enhancing Lysosomal Function Reduces Tau Pathology, Microglial Reactivity and Rescues Working Memory in 3xTg AD Mice.
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  Data: <searchLink fieldCode="AU" term="%22Mayeri+Z%22">Mayeri Z</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Woods+G%22">Woods G</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rane+A%22">Rane A</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kifle+A%22">Kifle A</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chamoli+M%22">Chamoli M</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shukla+S%22">Shukla S</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Walton+CC%22">Walton CC</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Andersen+JK%22">Andersen JK</searchLink>; Buck Institute for Research on Aging, Novato, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Nov 12. <i>Date of Electronic Publication: </i>2025 Nov 12.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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    Identifiers:
      – Type: doi
        Value: 10.1101/2025.11.09.687389
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      – Code: eng
        Text: English
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      – TitleFull: A Compound Enhancing Lysosomal Function Reduces Tau Pathology, Microglial Reactivity and Rescues Working Memory in 3xTg AD Mice.
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            NameFull: Mayeri Z
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            NameFull: Woods G
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              Text: 2025 Nov 12
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