Cell-free BRAFV600E levels predict progression-free survival in children with Langerhans cell histiocytosis treated with dabrafenib and maintenance chemotherapy.
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| Title: | Cell-free BRAFV600E levels predict progression-free survival in children with Langerhans cell histiocytosis treated with dabrafenib and maintenance chemotherapy. |
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| Authors: | Cui L; Laboratory of Hematologic Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Childrens Health, Beijing, China; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing., Wang D; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Zhao YZ; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Yao JF; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Wang CJ; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Zhao ZJ; Laboratory of Hematologic Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Childrens Health, Beijing, China; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing., Li WJ; Laboratory of Hematologic Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Childrens Health, Beijing, China; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing., Zhang Q; Laboratory of Hematologic Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Childrens Health, Beijing, China; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing., Lian HY; ., Ma HH; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Ge J; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Fang ZS; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Wang WQ; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Dong JJ; Laboratory of Hematologic Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Childrens Health, Beijing, China; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing., Wang TY; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing., Li ZG; Laboratory of Hematologic Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Childrens Health, Beijing, China; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing. ericlzg70@hotmail.com., Zhang R; National Key Discipline of Pediatrics, Capital Medical University, Beijing, China; Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China; Department of Hematology, Hematology center, Beijing Childrens Hospital, Capital Medical University, National Center for Childrens Health, Beijing. ruizh1973@126.com. |
| Source: | Haematologica [Haematologica] 2026 May 01; Vol. 111 (5), pp. 1786-1791. Date of Electronic Publication: 2025 Nov 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
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