Tolerance of Plasmodium falciparum mefloquine-resistant clinical isolates to mefloquine-piperaquine with implications for triple artemisinin-based combination therapies.
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| Title: | Tolerance of Plasmodium falciparum mefloquine-resistant clinical isolates to mefloquine-piperaquine with implications for triple artemisinin-based combination therapies. |
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| Authors: | Roesch C; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia.; Genetic and Biology of Plasmodium Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar., Cosson A; Laboratoire de Parasitologie-Mycologie, UR ESCAPE, Université de Rouen Normandie, Rouen, France., Mairet Khedim M; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Khim N; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Kloeung N; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Ke S; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Srun S; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Eam R; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Khean C; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Kul C; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia., Adoux L; GENOM'IC, Université Paris Cité, CNRS, INSERM, Institut Cochin, Paris, France., Popovici J; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia.; Infectious Disease Epidemiology and Analytics G5, Department of Global Health, Institut Pasteur, Université Paris Cité, INSERM U1347, Paris, France., Leang R; National Center for Parasitology, Entomology, and Malaria Control, Ministry of Health, Phnom Penh, Cambodia., Ringwald P; Mekong Malaria Elimination Programme, WHO, Phnom Penh, Cambodia., Ariey F; INSERM U1344, MERIT IRD, Université Paris Cité, Paris, France.; Service de Parasitologie-Mycologie, Hôpital Cochin, Paris, France., Coppée R; Laboratoire de Parasitologie-Mycologie, UR ESCAPE, Université de Rouen Normandie, Rouen, France.; Centre National de Référence du Paludisme, Laboratoire de Parasitologie-Mycologie, Hôpital Bichat-Claude Bernard, Paris, France.; Centre National de Référence Cryptosporidioses, microsporidies et autres protozooses digestives, Centre Hospitalier Universitaire de Rouen, Rouen, France., Witkowski B; Malaria Unit, Pasteur Institute of Cambodia, Phnom Penh, Cambodia. bwitkowski@pasteur.mg.; Infectious Disease Epidemiology and Analytics G5, Department of Global Health, Institut Pasteur, Université Paris Cité, INSERM U1347, Paris, France. bwitkowski@pasteur.mg.; Genetic and Biology of Plasmodium Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar. bwitkowski@pasteur.mg. |
| Source: | Nature communications [Nat Commun] 2025 Nov 27; Vol. 16 (1), pp. 10634. Date of Electronic Publication: 2025 Nov 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-65629-8 |
