3D genetic architecture of schizophrenia risk across three neuronal subtypes.

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Title: 3D genetic architecture of schizophrenia risk across three neuronal subtypes.
Authors: Powell SK; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Liao W; New York Genome Center, New York, NY, 10029, USA., Ghorbani S; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen, Norway., Rigat R; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., O'Shea C; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Kammourh S; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Elahi R; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Infante D; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Deans PJM; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA., Le DJ; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, 94305, USA., Agarwal P; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA., Qiang Seow W; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA., Balafkan N; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen, Norway., Wang KC; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA, 94304, USA., Akbarian S; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. schahram.akbarian@mssm.edu.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. schahram.akbarian@mssm.edu.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. schahram.akbarian@mssm.edu., Brennand KJ; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA. kristen.brennand@yale.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Apr; Vol. 31 (4), pp. 2216-2231. Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Powell+SK%22">Powell SK</searchLink>; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.<br /><searchLink fieldCode="AU" term="%22Liao+W%22">Liao W</searchLink>; New York Genome Center, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Ghorbani+S%22">Ghorbani S</searchLink>; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Rigat+R%22">Rigat R</searchLink>; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.<br /><searchLink fieldCode="AU" term="%22O'Shea+C%22">O'Shea C</searchLink>; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.<br /><searchLink fieldCode="AU" term="%22Kammourh+S%22">Kammourh S</searchLink>; 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Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.<br /><searchLink fieldCode="AU" term="%22Deans+PJM%22">Deans PJM</searchLink>; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.<br /><searchLink fieldCode="AU" term="%22Le+DJ%22">Le DJ</searchLink>; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Agarwal+P%22">Agarwal P</searchLink>; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Qiang+Seow+W%22">Qiang Seow W</searchLink>; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.<br /><searchLink fieldCode="AU" term="%22Balafkan+N%22">Balafkan N</searchLink>; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.; Mohn Research Centre for Regenerative Medicine, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Wang+KC%22">Wang KC</searchLink>; Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA, 94304, USA.<br /><searchLink fieldCode="AU" term="%22Akbarian+S%22">Akbarian S</searchLink>; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. schahram.akbarian@mssm.edu.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. schahram.akbarian@mssm.edu.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. schahram.akbarian@mssm.edu.<br /><searchLink fieldCode="AU" term="%22Brennand+KJ%22">Brennand KJ</searchLink>; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. kristen.brennand@yale.edu.; Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven, CT, 06511, USA. kristen.brennand@yale.edu.
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