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Limited predictive value of preoperative nigrosome integrity for motor outcomes in Parkinson's disease deep brain stimulation.

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Title: Limited predictive value of preoperative nigrosome integrity for motor outcomes in Parkinson's disease deep brain stimulation.
Authors: Hu CK; Department of Neurosurgery, Mackay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada., B Mohammed W; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada. Division of Neurology, University of Toronto, Toronto, ON, Canada., Bai Y; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.; Department of Neurosurgery, Beijing Tiantan Hospital, Beijing, China., Schmidt F; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.; Department of Neurosurgery, University Clinic Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany., Rodrigues TA; Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada., Kalia SK; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada., Fasano A; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada. Division of Neurology, University of Toronto, Toronto, ON, Canada.; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada., Germann J; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada., Alcaide-Leon P; Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Boutet A; Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada., Lozano AM; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada. Andres.Lozano@uhn.ca.; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada. Andres.Lozano@uhn.ca.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada. Andres.Lozano@uhn.ca.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2025 Nov 28; Vol. 11 (1), pp. 343. Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hu+CK%22">Hu CK</searchLink>; Department of Neurosurgery, Mackay Memorial Hospital, Taipei, Taiwan.; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22B+Mohammed+W%22">B Mohammed W</searchLink>; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada. Division of Neurology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bai+Y%22">Bai Y</searchLink>; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.; Department of Neurosurgery, Beijing Tiantan Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Schmidt+F%22">Schmidt F</searchLink>; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.; Department of Neurosurgery, University Clinic Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Rodrigues+TA%22">Rodrigues TA</searchLink>; Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Kalia+SK%22">Kalia SK</searchLink>; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada.; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Fasano+A%22">Fasano A</searchLink>; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada. Division of Neurology, University of Toronto, Toronto, ON, Canada.; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Germann+J%22">Germann J</searchLink>; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Alcaide-Leon+P%22">Alcaide-Leon P</searchLink>; Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Boutet+A%22">Boutet A</searchLink>; Joint Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Lozano+AM%22">Lozano AM</searchLink>; Department of Neurosurgery, Toronto Western Hospital, Toronto, ON, Canada. Andres.Lozano@uhn.ca.; Krembil Brain Institute, Toronto Western Hospital, University Health Network, Toronto, Canada. Andres.Lozano@uhn.ca.; Center for Advancing Neurotechnological Innovation to Application (CRANIA), Toronto, ON, Canada. Andres.Lozano@uhn.ca.
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              Text: 2025 Nov 28
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