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A systematic review and pharmacovigilance analysis of the risk of agranulocytosis associated with metamizole use.

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Title: A systematic review and pharmacovigilance analysis of the risk of agranulocytosis associated with metamizole use.
Authors: Zinzi A; Department of Life Science, Health, and Health Professions, Link Campus University, Via del Casale di San Pio V, 44-00165, Rome, Italy.; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy., Gaio M; Department of Life Science, Health, and Health Professions, Link Campus University, Via del Casale di San Pio V, 44-00165, Rome, Italy. m.gaio@unilink.it.; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy. m.gaio@unilink.it., Ruggiero D; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy., Riccardi C; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy., Cagnotta C; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy., Pentella C; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy., Capuano A; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy., Rafaniello C; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy.
Source: Scientific reports [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 42796. Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A systematic review and pharmacovigilance analysis of the risk of agranulocytosis associated with metamizole use.
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  Data: <searchLink fieldCode="AU" term="%22Zinzi+A%22">Zinzi A</searchLink>; Department of Life Science, Health, and Health Professions, Link Campus University, Via del Casale di San Pio V, 44-00165, Rome, Italy.; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Gaio+M%22">Gaio M</searchLink>; Department of Life Science, Health, and Health Professions, Link Campus University, Via del Casale di San Pio V, 44-00165, Rome, Italy. m.gaio@unilink.it.; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy. m.gaio@unilink.it.<br /><searchLink fieldCode="AU" term="%22Ruggiero+D%22">Ruggiero D</searchLink>; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Riccardi+C%22">Riccardi C</searchLink>; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Cagnotta+C%22">Cagnotta C</searchLink>; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Pentella+C%22">Pentella C</searchLink>; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Capuano+A%22">Capuano A</searchLink>; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Rafaniello+C%22">Rafaniello C</searchLink>; Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, 80138, Naples, Italy.; Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', 80138, Naples, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2025 Nov 28; Vol. 15 (1), pp. 42796. <i>Date of Electronic Publication: </i>2025 Nov 28.
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              Text: 2025 Nov 28
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