AGR2 suppresses ferroptosis via the p53/FPN1 regulatory axis and drives therapeutic vulnerabilities in pancreatic cancer.
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| Title: | AGR2 suppresses ferroptosis via the p53/FPN1 regulatory axis and drives therapeutic vulnerabilities in pancreatic cancer. |
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| Authors: | Jian Z; Department of Hematology and Oncology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China., Song J; Medical School, Southeast University, Nanjing, China., Lu L; Medical School, Southeast University, Nanjing, China., Pan T; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China., Zhang H; Medical School, Southeast University, Nanjing, China., Zhang Q; Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, China., Zhang W; Department of General Surgery, Zhongda Hospital, Medical School, Southeast University, Nanjing, China., Li R; Medical School, Southeast University, Nanjing, China., Gong J; Medical School, Southeast University, Nanjing, China., Shi N; Department of Urology, Northern Jiangsu People's Hospital, Yangzhou, China., Zuo S; Department of Hepatobiliary Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China. drzuosi@gzmu.edu.cn., Cheng T; Department of General Surgery, Zhongda Hospital, Medical School, Southeast University, Nanjing, China. chengtao860714@163.com., Yang Y; Department of Endocrinology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China. yangyuhong1008@126.com., Zhang Z; Division of Hepatobiliary and Transplantation Surgery, Department of General Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. zhangzhihengfly@163.com. |
| Source: | Cell death & disease [Cell Death Dis] 2025 Dec 01; Vol. 16 (1), pp. 877. Date of Electronic Publication: 2025 Dec 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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