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Phase II pilot randomized trial of zonisamide for disease modification in prodromal Lewy body disease.

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Title: Phase II pilot randomized trial of zonisamide for disease modification in prodromal Lewy body disease.
Authors: Hiraga K; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Hattori M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Tamakoshi D; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Satake Y; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Neurology, Daido Hospital, Nagoya, Japan., Fukushima T; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Saito Y; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Uematsu T; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Tsuboi T; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Sato M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan., Yokoi K; Department of Neurology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan., Suzuki K; Innovation Center for Translational Research, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan., Arahata Y; Department of Neurology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan., Ueki Y; Department of Rehabilitation Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Kinoshita F; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan., Matsuda H; Drug Discovery and Cyclotron Research Center, Southern Tohoku Research Institute for Neuroscience, Fukushima, Japan., Murata A; Affairs Department, Nihon Medi-Physics Co. Ltd., Tokyo, Japan., Yamamoto M; Kumiai Kosei Hospital, Takayama, Gifu, Japan., Wakai M; Chutoen General Medical Center, Kakegawa, Shizuoka, Japan., Matsukawa N; Department of Neurology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Washimi Y; Department of Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan., Katsuno M; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan. katsuno.masahisa.i1@f.mail.nagoya-u.ac.jp.; Department of Clinical Research Education, Nagoya University Graduate School of Medicine, Nagoya, Japan. katsuno.masahisa.i1@f.mail.nagoya-u.ac.jp.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2025 Dec 01; Vol. 11 (1), pp. 322. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase II pilot randomized trial of zonisamide for disease modification in prodromal Lewy body disease.
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  Data: <searchLink fieldCode="AU" term="%22Hiraga+K%22">Hiraga K</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Hattori+M%22">Hattori M</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Tamakoshi+D%22">Tamakoshi D</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Satake+Y%22">Satake Y</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Neurology, Daido Hospital, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Fukushima+T%22">Fukushima T</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Saito+Y%22">Saito Y</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Uematsu+T%22">Uematsu T</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Tsuboi+T%22">Tsuboi T</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+M%22">Sato M</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Yokoi+K%22">Yokoi K</searchLink>; Department of Neurology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+K%22">Suzuki K</searchLink>; Innovation Center for Translational Research, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Arahata+Y%22">Arahata Y</searchLink>; Department of Neurology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Ueki+Y%22">Ueki Y</searchLink>; Department of Rehabilitation Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Kinoshita+F%22">Kinoshita F</searchLink>; Department of Advanced Medicine, Nagoya University Hospital, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Matsuda+H%22">Matsuda H</searchLink>; Drug Discovery and Cyclotron Research Center, Southern Tohoku Research Institute for Neuroscience, Fukushima, Japan.<br /><searchLink fieldCode="AU" term="%22Murata+A%22">Murata A</searchLink>; Affairs Department, Nihon Medi-Physics Co. Ltd., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Yamamoto+M%22">Yamamoto M</searchLink>; Kumiai Kosei Hospital, Takayama, Gifu, Japan.<br /><searchLink fieldCode="AU" term="%22Wakai+M%22">Wakai M</searchLink>; Chutoen General Medical Center, Kakegawa, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Matsukawa+N%22">Matsukawa N</searchLink>; Department of Neurology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Washimi+Y%22">Washimi Y</searchLink>; Department of Comprehensive Care and Research on Memory Disorders, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Katsuno+M%22">Katsuno M</searchLink>; Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan. katsuno.masahisa.i1@f.mail.nagoya-u.ac.jp.; Department of Clinical Research Education, Nagoya University Graduate School of Medicine, Nagoya, Japan. katsuno.masahisa.i1@f.mail.nagoya-u.ac.jp.
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  Data: <searchLink fieldCode="JN" term="%22101675390%22">NPJ Parkinson's disease</searchLink> [NPJ Parkinsons Dis] 2025 Dec 01; Vol. 11 (1), pp. 322. <i>Date of Electronic Publication: </i>2025 Dec 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101675390 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2373-8057 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223738057%22">23738057 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Parkinsons Dis <i>Subsets: </i>PubMed not MEDLINE
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