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Alterations in Neuroinflammation, Microglia and Neuroplasticity in the Rat Hippocampus in a Combined Model of Periodontitis and Depression.

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Title: Alterations in Neuroinflammation, Microglia and Neuroplasticity in the Rat Hippocampus in a Combined Model of Periodontitis and Depression.
Authors: Robledo-Montaña J; Department of Pharmacology and Toxicology, Faculty of Medicine, Complutense University of Madrid (UCM), Hospital 12 de Octubre Research Institute (Imas12), Neurochemistry Research Institute UCM (IUIN), and REIS (Network of Stress Research), Madrid, Spain.; Biomedical Network Research Center of Mental Health (CIBERSAM), Institute of Health Carlos III, Madrid, Spain., Martín-Hernández D; Department of Pharmacology and Toxicology, Faculty of Medicine, Complutense University of Madrid (UCM), Hospital 12 de Octubre Research Institute (Imas12), Neurochemistry Research Institute UCM (IUIN), and REIS (Network of Stress Research), Madrid, Spain.; Biomedical Network Research Center of Mental Health (CIBERSAM), Institute of Health Carlos III, Madrid, Spain., Cuenca-Ortega J; Department of Pharmacology and Toxicology, Faculty of Medicine, Complutense University of Madrid (UCM), Hospital 12 de Octubre Research Institute (Imas12), Neurochemistry Research Institute UCM (IUIN), and REIS (Network of Stress Research), Madrid, Spain.; Biomedical Network Research Center of Mental Health (CIBERSAM), Institute of Health Carlos III, Madrid, Spain., Martínez M; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain.; Department of Dental Clinical Specialties, Faculty of Dentistry, UCM, Madrid, Spain., Virto L; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain.; Department of Anatomy and Embryology, Faculty of Optics and Optometry, UCM, Madrid, Spain., Ambrosio N; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain.; Department of Dental Clinical Specialties, Faculty of Dentistry, UCM, Madrid, Spain., Montero E; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain.; Department of Dental Clinical Specialties, Faculty of Dentistry, UCM, Madrid, Spain., Marín MJ; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain., Herrera D; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain.; Department of Dental Clinical Specialties, Faculty of Dentistry, UCM, Madrid, Spain., Sanz M; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain.; Department of Dental Clinical Specialties, Faculty of Dentistry, UCM, Madrid, Spain., Leza JC; Department of Pharmacology and Toxicology, Faculty of Medicine, Complutense University of Madrid (UCM), Hospital 12 de Octubre Research Institute (Imas12), Neurochemistry Research Institute UCM (IUIN), and REIS (Network of Stress Research), Madrid, Spain.; Biomedical Network Research Center of Mental Health (CIBERSAM), Institute of Health Carlos III, Madrid, Spain., Figuero E; ETEP (Etiology and Therapy of Periodontal and Peri-Implant Diseases) Research Group, UCM, Madrid, Spain.; Department of Dental Clinical Specialties, Faculty of Dentistry, UCM, Madrid, Spain., García-Bueno B; Department of Pharmacology and Toxicology, Faculty of Medicine, Complutense University of Madrid (UCM), Hospital 12 de Octubre Research Institute (Imas12), Neurochemistry Research Institute UCM (IUIN), and REIS (Network of Stress Research), Madrid, Spain.; Biomedical Network Research Center of Mental Health (CIBERSAM), Institute of Health Carlos III, Madrid, Spain.
Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2025 Dec; Vol. 31 (12), pp. e70669.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949 (Electronic) Linking ISSN: 17555930 NLM ISO Abbreviation: CNS Neurosci Ther Subsets: MEDLINE
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