The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma.
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| Title: | The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma. |
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| Authors: | Hill LA; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Scott RW; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Martin LA; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Arostegui M; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Davenport G; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Vemon M; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Hofvander J; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden., Wang XQ; Department of Pathology, University of British Columbia and BC Cancer, Vancouver, BC, Canada., Li J; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, Huntsman Cancer Institute, Salt Lake City, UT, USA., Nielsen TO; Department of Pathology, University of British Columbia and BC Cancer, Vancouver, BC, Canada., Jones KB; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, Huntsman Cancer Institute, Salt Lake City, UT, USA., Hirst M; Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada., Underhill TM; Biomedical Research Centre, Vancouver, BC, Canada. tunderhi@brc.ubc.ca.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada. tunderhi@brc.ubc.ca. |
| Source: | Nature communications [Nat Commun] 2025 Dec 02; Vol. 16 (1), pp. 10830. Date of Electronic Publication: 2025 Dec 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-65850-5 |
