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The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma.

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Title: The fibroblast epigenome underlies SS18::SSX-mediated transformation in synovial sarcoma.
Authors: Hill LA; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Scott RW; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Martin LA; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Arostegui M; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Davenport G; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Vemon M; Biomedical Research Centre, Vancouver, BC, Canada.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada., Hofvander J; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden., Wang XQ; Department of Pathology, University of British Columbia and BC Cancer, Vancouver, BC, Canada., Li J; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, Huntsman Cancer Institute, Salt Lake City, UT, USA., Nielsen TO; Department of Pathology, University of British Columbia and BC Cancer, Vancouver, BC, Canada., Jones KB; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA.; Department of Oncological Sciences, Huntsman Cancer Institute, Salt Lake City, UT, USA., Hirst M; Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada., Underhill TM; Biomedical Research Centre, Vancouver, BC, Canada. tunderhi@brc.ubc.ca.; Department of Cellular and Physiological Sciences, University of British Columbia, Vancouver, BC, Canada. tunderhi@brc.ubc.ca.
Source: Nature communications [Nat Commun] 2025 Dec 02; Vol. 16 (1), pp. 10830. Date of Electronic Publication: 2025 Dec 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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