Novel bis(triazole) analogues as selective TGR5 agonists with anti-diabesity effects.
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| Title: | Novel bis(triazole) analogues as selective TGR5 agonists with anti-diabesity effects. |
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| Authors: | Saxena A; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Jawaharlal Nehru University (JNU), New Delhi 110067, India., Kaushik D; Neuroscience and Ageing Biology Division, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Jawaharlal Nehru University (JNU), New Delhi 110067, India., Kumar BA; Neuroscience and Ageing Biology Division, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Jawaharlal Nehru University (JNU), New Delhi 110067, India., Rathaur S; Pharmaceutics & Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Jawaharlal Nehru University (JNU), New Delhi 110067, India., Chand D; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P. 201002, India., Srivastava KR; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P. 201002, India., Gayen JR; Pharmaceutics & Pharmacokinetics Division, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P. 201002, India., Yadav PN; Neuroscience and Ageing Biology Division, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P. 201002, India. Electronic address: pn.yadav@cdri.res.in., Ghosh N; Division of Medicinal and Process Chemistry, CSIR-Central Drug Research Institute, Lucknow, U.P. 226031, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, U.P. 201002, India. Electronic address: nayan.ghosh@cdri.res.in. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2026 Jan; Vol. 168, pp. 109286. Date of Electronic Publication: 2025 Nov 22. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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