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Astaxanthin alleviates DSS-induced ulcerative colitis in mice associated with Nrf2-mediated ferroptosis independently of gut microbiota modulation.

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Title: Astaxanthin alleviates DSS-induced ulcerative colitis in mice associated with Nrf2-mediated ferroptosis independently of gut microbiota modulation.
Authors: Wei MX; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China; Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian Province, PR China., Wu XY; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China., Lin JW; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China., Huang JY; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China., Cheng J; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China., Huang WF; Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian Province, PR China. Electronic address: hwf0625@xmu.edu.cn., Xu GH; Xiamen Medicine Research Institute, Xiamen, Fujian Province, PR China. Electronic address: xghcxm@163.com., Yi LT; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China; Institute of Pharmaceutical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China; Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen, Fujian Province 361021, PR China. Electronic address: litaoyi@hqu.edu.cn.
Source: The Journal of nutritional biochemistry [J Nutr Biochem] 2026 Mar; Vol. 149, pp. 110212. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Astaxanthin alleviates DSS-induced ulcerative colitis in mice associated with Nrf2-mediated ferroptosis independently of gut microbiota modulation.
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  Data: <searchLink fieldCode="AU" term="%22Wei+MX%22">Wei MX</searchLink>; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China; Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian Province, PR China.<br /><searchLink fieldCode="AU" term="%22Wu+XY%22">Wu XY</searchLink>; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China.<br /><searchLink fieldCode="AU" term="%22Lin+JW%22">Lin JW</searchLink>; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China.<br /><searchLink fieldCode="AU" term="%22Huang+JY%22">Huang JY</searchLink>; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China.<br /><searchLink fieldCode="AU" term="%22Cheng+J%22">Cheng J</searchLink>; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China.<br /><searchLink fieldCode="AU" term="%22Huang+WF%22">Huang WF</searchLink>; Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian Province, PR China. Electronic address: hwf0625@xmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Xu+GH%22">Xu GH</searchLink>; Xiamen Medicine Research Institute, Xiamen, Fujian Province, PR China. Electronic address: xghcxm@163.com.<br /><searchLink fieldCode="AU" term="%22Yi+LT%22">Yi LT</searchLink>; Department of Chemical and Pharmaceutical Engineering, College of Chemical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China; Institute of Pharmaceutical Engineering, Huaqiao University, Xiamen, Fujian Province, PR China; Fujian Provincial Key Laboratory of Biochemical Technology, Huaqiao University, Xiamen, Fujian Province 361021, PR China. Electronic address: litaoyi@hqu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229010081%22">The Journal of nutritional biochemistry</searchLink> [J Nutr Biochem] 2026 Mar; Vol. 149, pp. 110212. <i>Date of Electronic Publication: </i>2025 Dec 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9010081 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4847 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209552863%22">09552863 </searchLink><i>NLM ISO Abbreviation: </i>J Nutr Biochem <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.jnutbio.2025.110212
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      – Code: eng
        Text: English
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        StartPage: 110212
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      – TitleFull: Astaxanthin alleviates DSS-induced ulcerative colitis in mice associated with Nrf2-mediated ferroptosis independently of gut microbiota modulation.
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            NameFull: Cheng J
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            – D: 01
              M: 03
              Text: 2026 Mar
              Type: published
              Y: 2026
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              Value: 149
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