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High specificity of MsmCAR toward 4-hydroxyvaleric acid enables efficient 1,4-pentanediol production from biomass-derived levulinic acid.

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Title: High specificity of MsmCAR toward 4-hydroxyvaleric acid enables efficient 1,4-pentanediol production from biomass-derived levulinic acid.
Authors: Choi S; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea., Lee SH; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea., Kim Y; Biotechnology Process Engineering Center, KRIBB, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si 28116, Republic of Korea; Bioprocess Department, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea., Jeon WY; Biotechnology Process Engineering Center, KRIBB, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si 28116, Republic of Korea; Bioprocess Department, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea., Ahn JO; Biotechnology Process Engineering Center, KRIBB, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si 28116, Republic of Korea; Bioprocess Department, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea., Bhatia SK; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea; Institute for Ubiquitous Information Technology and Applications, Konkuk University, Seoul, Republic of Korea., Choi KY; Department of Molecular Science and Technology, Ajou University, Suwon, Gyeonggi-do, South Korea; Advanced College of Bio-Convergence Engineering, Ajou University, Suwon, Gyeonggi-do, Republic of Korea., Joo JC; Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do, Republic of Korea. Electronic address: jcjoo@khu.ac.kr., Yang YH; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea; Institute for Ubiquitous Information Technology and Applications, Konkuk University, Seoul, Republic of Korea. Electronic address: seokor@konkuk.ac.kr.
Source: Journal of biotechnology [J Biotechnol] 2026 Feb; Vol. 410, pp. 115-124. Date of Electronic Publication: 2025 Dec 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8411927 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4863 (Electronic) Linking ISSN: 01681656 NLM ISO Abbreviation: J Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High specificity of MsmCAR toward 4-hydroxyvaleric acid enables efficient 1,4-pentanediol production from biomass-derived levulinic acid.
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  Data: <searchLink fieldCode="AU" term="%22Choi+S%22">Choi S</searchLink>; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; Biotechnology Process Engineering Center, KRIBB, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si 28116, Republic of Korea; Bioprocess Department, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+WY%22">Jeon WY</searchLink>; Biotechnology Process Engineering Center, KRIBB, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si 28116, Republic of Korea; Bioprocess Department, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+JO%22">Ahn JO</searchLink>; Biotechnology Process Engineering Center, KRIBB, 30 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju-si 28116, Republic of Korea; Bioprocess Department, University of Science and Technology, 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Bhatia+SK%22">Bhatia SK</searchLink>; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea; Institute for Ubiquitous Information Technology and Applications, Konkuk University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+KY%22">Choi KY</searchLink>; Department of Molecular Science and Technology, Ajou University, Suwon, Gyeonggi-do, South Korea; Advanced College of Bio-Convergence Engineering, Ajou University, Suwon, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Joo+JC%22">Joo JC</searchLink>; Department of Chemical Engineering, Kyung Hee University, Gyeonggi-do, Republic of Korea. Electronic address: jcjoo@khu.ac.kr.<br /><searchLink fieldCode="AU" term="%22Yang+YH%22">Yang YH</searchLink>; Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea; Institute for Ubiquitous Information Technology and Applications, Konkuk University, Seoul, Republic of Korea. Electronic address: seokor@konkuk.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%228411927%22">Journal of biotechnology</searchLink> [J Biotechnol] 2026 Feb; Vol. 410, pp. 115-124. <i>Date of Electronic Publication: </i>2025 Dec 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Publishers%22">Elsevier Science Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8411927 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4863 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201681656%22">01681656 </searchLink><i>NLM ISO Abbreviation: </i>J Biotechnol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jbiotec.2025.11.020
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      – Code: eng
        Text: English
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              Text: 2026 Feb
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