Transtympanic sodium thiosulphate to prevent cisplatin-related hearing loss: a protocol for randomised controlled multicentre phase III trial, the SOUND trial.
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| Title: | Transtympanic sodium thiosulphate to prevent cisplatin-related hearing loss: a protocol for randomised controlled multicentre phase III trial, the SOUND trial. |
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| Authors: | Burger AVM; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands.; Department of Otorhinolaryngology - Head and Neck surgery, Leiden University Medical Center, Leiden, Netherlands., Duinkerken CW; Department of Otorhinolaryngology - Head and Neck surgery, Leiden University Medical Center, Leiden, Netherlands.; Department of Otolaryngology, Medical Centre Haaglanden, The Hague, ZH, Netherlands., Jansen JC; Department of Otorhinolaryngology - Head and Neck surgery, Leiden University Medical Center, Leiden, Netherlands., Keereweer S; Department of Otolaryngology and Head and Neck Surgery, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands., Cals FL; Department of Otorhinolaryngology, Radboud University Medical Center, Nijmegen, GE, Netherlands., Stokroos RJ; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Centre Utrecht, Utrecht, Netherlands., de Boer JP; Department of Medical Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands., Exterkate L; Department of Radiation Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands., van der Velden LA; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands., Hoetink AE; Department of Otorhinolaryngology-Head and Neck Surgery, University Medical Centre Utrecht, Utrecht, Netherlands., Nuijen B; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands., Hauptmann M; Biometrie und Registerforschung, Brandenburg Medical School Theodor Fontane, Neuruppin, Brandenburg, Germany., van Sluis KE; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands., Bruintjes TD; Department of Otorhinolaryngology - Head and Neck surgery, Leiden University Medical Center, Leiden, Netherlands.; Gelre Hospitals, Apeldoorn, GE, Netherlands., Zuur CL; Department of Head and Neck Surgery and Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands c.zuur@nki.nl.; Department of Otorhinolaryngology - Head and Neck surgery, Leiden University Medical Center, Leiden, Netherlands. |
| Source: | BMJ open [BMJ Open] 2025 Dec 03; Vol. 15 (12), pp. e107101. Date of Electronic Publication: 2025 Dec 03. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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