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Efficacy and safety of irinotecan-based therapy in elderly patients with advanced gastric cancer receiving third-line or later chemotherapy: post-hoc age-subgroup analysis of the rindberg trial.

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Title: Efficacy and safety of irinotecan-based therapy in elderly patients with advanced gastric cancer receiving third-line or later chemotherapy: post-hoc age-subgroup analysis of the rindberg trial.
Authors: Kawabata R; Osaka Rosai Hospital, Sakai, Japan. r-kawabata@umin.ac.jp.; Department of Surgery, Sakai City Medical Center, 1-1-1, Ebaraji-Cho, Nishi-Ku, Sakai-City, Osaka, 5938304, Japan. r-kawabata@umin.ac.jp., Sakai D; The University of Osaka Hospital, Suita, Japan.; Osaka International Cancer Institute, Osaka, Japan., Shimokawa T; Wakayama Medical University, Wakayama, Japan., Kizawa R; Toranomon Hospital, Tokyo, Japan., Ishiguro T; Saitama Medical Center, Saitama Medical University, Saitama, Japan., Yukami H; Osaka Medical and Pharmaceutical University, Osaka, Japan., Boku S; Kansai Medical University Hospital, Hirakata, Japan., Yamaguchi T; Osaka Medical and Pharmaceutical University, Osaka, Japan., Endo S; Kawasaki Medical School, Kurashiki, Japan., Tsujinaka T; Izumi City General Hospital, Osaka, Japan., Satoh T; The University of Osaka Hospital, Suita, Japan.
Source: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association [Gastric Cancer] 2026 Jan; Vol. 29 (1), pp. 220-229. Date of Electronic Publication: 2025 Dec 04.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 100886238 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1436-3305 (Electronic) Linking ISSN: 14363291 NLM ISO Abbreviation: Gastric Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of irinotecan-based therapy in elderly patients with advanced gastric cancer receiving third-line or later chemotherapy: post-hoc age-subgroup analysis of the rindberg trial.
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  Data: <searchLink fieldCode="AU" term="%22Kawabata+R%22">Kawabata R</searchLink>; Osaka Rosai Hospital, Sakai, Japan. r-kawabata@umin.ac.jp.; Department of Surgery, Sakai City Medical Center, 1-1-1, Ebaraji-Cho, Nishi-Ku, Sakai-City, Osaka, 5938304, Japan. r-kawabata@umin.ac.jp.<br /><searchLink fieldCode="AU" term="%22Sakai+D%22">Sakai D</searchLink>; The University of Osaka Hospital, Suita, Japan.; Osaka International Cancer Institute, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Shimokawa+T%22">Shimokawa T</searchLink>; Wakayama Medical University, Wakayama, Japan.<br /><searchLink fieldCode="AU" term="%22Kizawa+R%22">Kizawa R</searchLink>; Toranomon Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Ishiguro+T%22">Ishiguro T</searchLink>; Saitama Medical Center, Saitama Medical University, Saitama, Japan.<br /><searchLink fieldCode="AU" term="%22Yukami+H%22">Yukami H</searchLink>; Osaka Medical and Pharmaceutical University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Boku+S%22">Boku S</searchLink>; Kansai Medical University Hospital, Hirakata, Japan.<br /><searchLink fieldCode="AU" term="%22Yamaguchi+T%22">Yamaguchi T</searchLink>; Osaka Medical and Pharmaceutical University, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Endo+S%22">Endo S</searchLink>; Kawasaki Medical School, Kurashiki, Japan.<br /><searchLink fieldCode="AU" term="%22Tsujinaka+T%22">Tsujinaka T</searchLink>; Izumi City General Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Satoh+T%22">Satoh T</searchLink>; The University of Osaka Hospital, Suita, Japan.
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  Data: <searchLink fieldCode="JN" term="%22100886238%22">Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association</searchLink> [Gastric Cancer] 2026 Jan; Vol. 29 (1), pp. 220-229. <i>Date of Electronic Publication: </i>2025 Dec 04.
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  Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag+Tokyo%22">Springer-Verlag Tokyo </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>100886238 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1436-3305 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214363291%22">14363291 </searchLink><i>NLM ISO Abbreviation: </i>Gastric Cancer <i>Subsets: </i>MEDLINE
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              Text: 2026 Jan
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