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Single cell mapping identifies a distinct platelet-phenotype in psoriatic type III inflammation.

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Title: Single cell mapping identifies a distinct platelet-phenotype in psoriatic type III inflammation.
Authors: Kommoss KS; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany., Krishnarajah S; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland.; Roche Pharma Research and Early Development, Strategy, Portfolio and Operations, Roche Innovation Center Basel, F.Hoffmann-La Roche Ltd, Grenzacherstrasse 124, Basel, Switzerland., Bieler T; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany., Friebel E; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland.; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany., Rindlisbacher L; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland., Ramadori P; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Häne P; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland., Kam S; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Müller F; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Prokosch S; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Rothermel U; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Wu Y; Institute for Immunology, University Hospital Heidelberg, Heidelberg, Germany., Barletta F; Quantitative Biology Center (QBiC), University of Tübingen, Tübingen, Germany.; The M3 Research Centre, Medical faculty Tübingen, Tübingen, Germany., Czemmel S; Quantitative Biology Center (QBiC), University of Tübingen, Tübingen, Germany.; The M3 Research Centre, Medical faculty Tübingen, Tübingen, Germany., Nahnsen S; Quantitative Biology Center (QBiC), University of Tübingen, Tübingen, Germany.; Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University, Tübingen, Germany., Helm D; Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany., Schneider M; Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany., Schäkel K; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany., Enk A; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany., Becher B; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland. becher@immunology.uzh.ch., Heikenwälder M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. mathias.heikenwaelder@med.uni-tuebingen.de.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University, Tübingen, Germany. mathias.heikenwaelder@med.uni-tuebingen.de.; Institute for Interdisciplinary Research on Cancer Metabolism and Chronic Inflammation, The M3 Research Centre, Medical faculty Tübingen, Tübingen, Germany. mathias.heikenwaelder@med.uni-tuebingen.de.
Source: Nature communications [Nat Commun] 2025 Dec 05; Vol. 16 (1), pp. 10881. Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kommoss+KS%22">Kommoss KS</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Krishnarajah+S%22">Krishnarajah S</searchLink>; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland.; Roche Pharma Research and Early Development, Strategy, Portfolio and Operations, Roche Innovation Center Basel, F.Hoffmann-La Roche Ltd, Grenzacherstrasse 124, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bieler+T%22">Bieler T</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Friebel+E%22">Friebel E</searchLink>; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland.; Department of Neuropathology, Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Rindlisbacher+L%22">Rindlisbacher L</searchLink>; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ramadori+P%22">Ramadori P</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Häne+P%22">Häne P</searchLink>; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kam+S%22">Kam S</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+F%22">Müller F</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Prokosch+S%22">Prokosch S</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Rothermel+U%22">Rothermel U</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Institute for Immunology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Barletta+F%22">Barletta F</searchLink>; Quantitative Biology Center (QBiC), University of Tübingen, Tübingen, Germany.; The M3 Research Centre, Medical faculty Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Czemmel+S%22">Czemmel S</searchLink>; Quantitative Biology Center (QBiC), University of Tübingen, Tübingen, Germany.; The M3 Research Centre, Medical faculty Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Nahnsen+S%22">Nahnsen S</searchLink>; Quantitative Biology Center (QBiC), University of Tübingen, Tübingen, Germany.; Institute for Bioinformatics and Medical Informatics, University of Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Helm+D%22">Helm D</searchLink>; Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider+M%22">Schneider M</searchLink>; Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Schäkel+K%22">Schäkel K</searchLink>; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Enk+A%22">Enk A</searchLink>; Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Becher+B%22">Becher B</searchLink>; Institute of Experimental Immunology, University of Zurich, 8057, Zurich, Switzerland. becher@immunology.uzh.ch.<br /><searchLink fieldCode="AU" term="%22Heikenwälder+M%22">Heikenwälder M</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. mathias.heikenwaelder@med.uni-tuebingen.de.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University, Tübingen, Germany. mathias.heikenwaelder@med.uni-tuebingen.de.; Institute for Interdisciplinary Research on Cancer Metabolism and Chronic Inflammation, The M3 Research Centre, Medical faculty Tübingen, Tübingen, Germany. mathias.heikenwaelder@med.uni-tuebingen.de.
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