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International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative.

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Title: International consensus for the assessment of social cognition in neurocognitive disorders: framework definition and clinical recommendations of the SIGNATURE initiative.
Authors: Dodich A; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy. alessandra.dodich@unitn.it., Panzavolta A; IUSS Cognitive Neuroscience (ICoN) Center, Scuola Universitaria Superiore IUSS Di Pavia, Pavia, Italy., Funghi G; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy., Meli C; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy., Festari C; Laboratory of Alzheimer's Neuroimaging and Epidemiology, IRCCS Istituto Centro San Giovanni Di Dio Fatebenefratelli, Brescia, Italy., Chatzikostopoulos T; Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece., Chicherio C; Memory Center, Geneva University Hospitals, Geneva, Switzerland., Clarens F; Memory and Aging Center, Fleni, Buenos Aires, Argentina., de Oliveira FF; Universidade Federal de São Paulo, São Paulo, Brazil., Filardi M; University for Foreigners of Perugia, Perugia, Italy., Ibanez A; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibáñez, Santiago, Chile.; Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland.; Department of Biophysics, School of Medicine, Istanbul Medipol University, 34815, Istanbul, Türkiye.; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, 08005, Barcelona, Spain.; Cognitive Neuroscience Center (CNC), Universidad de San Andrés, Buenos Aires, Argentina., Invernizzi L; Italian Frontotemporal Dementia Association, AIMFT, Brescia, Italy., Lebouvier T; Université de Lille, Inserm, Centre Hospitalier Universitaire de Lille, Lille Neuroscience & Cognition, Lille, France., Logroscino G; Università Degli Studi Di Bari Aldo Moro, Bari, Italy., MacPherson SE; Department of Psychology, The University of Edinburgh, Edinburgh, UK., Manca R; Department of Medicine and Surgery, University of Parma, Parma, Italy., Marra C; Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Department of Psychology - Catholic University of Sacred Heart, Milan, Italy., Matias-Guiu JA; Department of Neurology, Hospital Clinico San Carlos. San Carlos Health Research Institute (IdISSC), Universidad Complutense, Madrid, Spain., Montembeault M; Douglas Research Centre & Department of Psychiatry, McGill University, Montreal, Canada., Papagno C; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy., Pomati S; Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy., Possenti M; Federazione Alzheimer Italia, Milan, Italy., Piguet O; School of Psychology and Brain & Mind Centre, University of Sydney, Sydney, Australia., Sacco L; Neuropsychological and Speech Therapy Unit, Neurocenter of Southern Switzerland, Lugano, Switzerland., Schild AK; Universitätsklinikum Köln, Cologne, Germany., Sollberger M; Memory Clinic, University Department of Geriatric Medicine FELIX PLATTER, Basel, Switzerland., Tábuas-Pereira M; Memory Clinic, Neurology Department, Centro Hospitalar E Universitário de Coimbra, Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal., Tsatali M; Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece., Tsolaki M; Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece., van den Berg E; Department of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands., Cappa SF; IUSS Cognitive Neuroscience (ICoN) Center, Scuola Universitaria Superiore IUSS Di Pavia, Pavia, Italy., Bertoux M; Lille Neuroscience & Cognition, Inserm U1172, Univ Lille, CHU Lille, France., Kumfor F; School of Psychology, University of Sydney, Sydney, NSW, Australia., Van den Stock J; Neuropsychiatry, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Boccardi M; German Centre for Neurodegenerative Diseases (DZNE), Rostock-Greifswald Site, Rostock, Germany.; Centre of Competence On Ageing, Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern Switzerland, Manno, Switzerland.; Department of Psychosomatic Medicine and Psychotherapy, University Medicine Rostock, 18147, Gehlsheimer Str. 20, Rostock, Germany., Welsh-Bohmer KA; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA., Cerami C; IUSS Cognitive Neuroscience (ICoN) Center, Scuola Universitaria Superiore IUSS Di Pavia, Pavia, Italy.; Istituti Clinici Scientifici Maugeri IRCCS, Brain e-Health Aging Laboratory, Department of Neurorehabilitation, Milan, Italy.
Corporate Authors: SIGNATURE Consortium
Source: Alzheimer's research & therapy [Alzheimers Res Ther] 2025 Dec 06; Vol. 18 (1), pp. 6. Date of Electronic Publication: 2025 Dec 06.
Publication Type: Journal Article; Consensus Statement
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Dodich+A%22">Dodich A</searchLink>; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy. alessandra.dodich@unitn.it.<br /><searchLink fieldCode="AU" term="%22Panzavolta+A%22">Panzavolta A</searchLink>; IUSS Cognitive Neuroscience (ICoN) Center, Scuola Universitaria Superiore IUSS Di Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Funghi+G%22">Funghi G</searchLink>; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy.<br /><searchLink fieldCode="AU" term="%22Meli+C%22">Meli C</searchLink>; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy.<br /><searchLink fieldCode="AU" term="%22Festari+C%22">Festari C</searchLink>; Laboratory of Alzheimer's Neuroimaging and Epidemiology, IRCCS Istituto Centro San Giovanni Di Dio Fatebenefratelli, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Chatzikostopoulos+T%22">Chatzikostopoulos T</searchLink>; Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Chicherio+C%22">Chicherio C</searchLink>; Memory Center, Geneva University Hospitals, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Clarens+F%22">Clarens F</searchLink>; Memory and Aging Center, Fleni, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+FF%22">de Oliveira FF</searchLink>; Universidade Federal de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Filardi+M%22">Filardi M</searchLink>; University for Foreigners of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Ibanez+A%22">Ibanez A</searchLink>; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibáñez, Santiago, Chile.; Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland.; Department of Biophysics, School of Medicine, Istanbul Medipol University, 34815, Istanbul, Türkiye.; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, 08005, Barcelona, Spain.; Cognitive Neuroscience Center (CNC), Universidad de San Andrés, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Invernizzi+L%22">Invernizzi L</searchLink>; Italian Frontotemporal Dementia Association, AIMFT, Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Lebouvier+T%22">Lebouvier T</searchLink>; Université de Lille, Inserm, Centre Hospitalier Universitaire de Lille, Lille Neuroscience & Cognition, Lille, France.<br /><searchLink fieldCode="AU" term="%22Logroscino+G%22">Logroscino G</searchLink>; Università Degli Studi Di Bari Aldo Moro, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22MacPherson+SE%22">MacPherson SE</searchLink>; Department of Psychology, The University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Manca+R%22">Manca R</searchLink>; Department of Medicine and Surgery, University of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Marra+C%22">Marra C</searchLink>; Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Department of Psychology - Catholic University of Sacred Heart, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Matias-Guiu+JA%22">Matias-Guiu JA</searchLink>; Department of Neurology, Hospital Clinico San Carlos. San Carlos Health Research Institute (IdISSC), Universidad Complutense, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Montembeault+M%22">Montembeault M</searchLink>; Douglas Research Centre & Department of Psychiatry, McGill University, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Papagno+C%22">Papagno C</searchLink>; Center for Mind/Brain Sciences - CIMeC, University of Trento, Rovereto, Italy.<br /><searchLink fieldCode="AU" term="%22Pomati+S%22">Pomati S</searchLink>; Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Possenti+M%22">Possenti M</searchLink>; Federazione Alzheimer Italia, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Piguet+O%22">Piguet O</searchLink>; School of Psychology and Brain & Mind Centre, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Sacco+L%22">Sacco L</searchLink>; Neuropsychological and Speech Therapy Unit, Neurocenter of Southern Switzerland, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schild+AK%22">Schild AK</searchLink>; Universitätsklinikum Köln, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Sollberger+M%22">Sollberger M</searchLink>; Memory Clinic, University Department of Geriatric Medicine FELIX PLATTER, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tábuas-Pereira+M%22">Tábuas-Pereira M</searchLink>; Memory Clinic, Neurology Department, Centro Hospitalar E Universitário de Coimbra, Coimbra, Portugal.; Faculty of Medicine, University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Tsatali+M%22">Tsatali M</searchLink>; Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Tsolaki+M%22">Tsolaki M</searchLink>; Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22van+den+Berg+E%22">van den Berg E</searchLink>; Department of Neurology and Alzheimer Center Erasmus MC, Erasmus MC University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Cappa+SF%22">Cappa SF</searchLink>; IUSS Cognitive Neuroscience (ICoN) Center, Scuola Universitaria Superiore IUSS Di Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Bertoux+M%22">Bertoux M</searchLink>; Lille Neuroscience & Cognition, Inserm U1172, Univ Lille, CHU Lille, France.<br /><searchLink fieldCode="AU" term="%22Kumfor+F%22">Kumfor F</searchLink>; School of Psychology, University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Van+den+Stock+J%22">Van den Stock J</searchLink>; Neuropsychiatry, Leuven Brain Institute, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Boccardi+M%22">Boccardi M</searchLink>; German Centre for Neurodegenerative Diseases (DZNE), Rostock-Greifswald Site, Rostock, Germany.; Centre of Competence On Ageing, Department of Business Economics, Health and Social Care, University of Applied Sciences and Arts of Southern Switzerland, Manno, Switzerland.; Department of Psychosomatic Medicine and Psychotherapy, University Medicine Rostock, 18147, Gehlsheimer Str. 20, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Welsh-Bohmer+KA%22">Welsh-Bohmer KA</searchLink>; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Cerami+C%22">Cerami C</searchLink>; IUSS Cognitive Neuroscience (ICoN) Center, Scuola Universitaria Superiore IUSS Di Pavia, Pavia, Italy.; Istituti Clinici Scientifici Maugeri IRCCS, Brain e-Health Aging Laboratory, Department of Neurorehabilitation, Milan, Italy.
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