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Early severe immune-related pneumonitis, hepatitis, and agranulocytosis with radiographic response in sarcomatoid malignant pleural mesothelioma treated with nivolumab and ipilimumab: a case report highlighting dual liver biopsies and rechallenge decision-making.

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Title: Early severe immune-related pneumonitis, hepatitis, and agranulocytosis with radiographic response in sarcomatoid malignant pleural mesothelioma treated with nivolumab and ipilimumab: a case report highlighting dual liver biopsies and rechallenge decision-making.
Authors: Oba T; Department of Respiratory Medicine, Japanese Red Cross Saitama Hospital, 1-5 Shintoshin, Chuo-ku, Saitama City, Saitama, Japan., Itogawa K; Department of Respiratory Medicine, National Hospital Organization Tokyo National Hospital, Tokyo, Japan.; Department of Respiratory Medicine, Japanese Red Cross Saitama Hospital, Saitama, Japan., Machida Y; Department of Respiratory Medicine, Japanese Red Cross Saitama Hospital, Saitama, Japan., Ono Y; Department of Gastrointestinal Medicine, Japanese Red Cross Saitama Hospital, Saitama, Japan., Morita Y; Department of Gastrointestinal Medicine, Japanese Red Cross Saitama Hospital, Saitama, Japan., Nakatani D; Department of Respiratory Medicine, Japanese Red Cross Saitama Hospital, Saitama, Japan., Akasaka K; Department of Respiratory Medicine, Japanese Red Cross Saitama Hospital, Saitama, Japan., Adachi A; Department of Pathology, Japanese Red Cross Saitama Hospital, Saitama, Japan., Matsushima H; Department of Respiratory Medicine, Japanese Red Cross Saitama Hospital, Saitama, Japan.
Source: Therapeutic advances in medical oncology [Ther Adv Med Oncol] 2025 Dec 04; Vol. 17, pp. 17588359251397331. Date of Electronic Publication: 2025 Dec 04 (Print Publication: 2025).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Sage Country of Publication: England NLM ID: 101510808 Publication Model: eCollection Cited Medium: Print ISSN: 1758-8340 (Print) Linking ISSN: 17588340 NLM ISO Abbreviation: Ther Adv Med Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Early severe immune-related pneumonitis, hepatitis, and agranulocytosis with radiographic response in sarcomatoid malignant pleural mesothelioma treated with nivolumab and ipilimumab: a case report highlighting dual liver biopsies and rechallenge decision-making.
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              Text: 2025 Dec 04
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