Bovine viral diarrhea virus suppresses type I IFN production by inducing MAVS degradation via autophagy mediated by the ROS-endoplasmic reticulum stress axis.

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Title: Bovine viral diarrhea virus suppresses type I IFN production by inducing MAVS degradation via autophagy mediated by the ROS-endoplasmic reticulum stress axis.
Authors: Wang J; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Zhou J; College of Animal Science, Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China., Wang Y; Key Laboratory of Medical Molecular Virology of the Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, China., Fan W; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Xia X; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Chen J; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Zhu H; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Wang Q; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Li X; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Liu Y; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Xiang J; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Yu H; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Mao M; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Xu R; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Liu J; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China., Jia S; Key Laboratory for Animal Disease Control and Pharmaceutical Development of Heilongjiang Province, Northeast Agricultural University, Harbin, People's Republic of China., Li Y; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.; College of Animal Science, Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China., Xu Y; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.; College of Animal Science, Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Source: Journal of virology [J Virol] 2026 Jan 20; Vol. 100 (1), pp. e0164325. Date of Electronic Publication: 2025 Dec 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bovine viral diarrhea virus suppresses type I IFN production by inducing MAVS degradation via autophagy mediated by the ROS-endoplasmic reticulum stress axis.
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  Data: <searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhou+J%22">Zhou J</searchLink>; College of Animal Science, Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Key Laboratory of Medical Molecular Virology of the Ministry of Education, School of Basic Medical Sciences, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Fan+W%22">Fan W</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xia+X%22">Xia X</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xiang+J%22">Xiang J</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yu+H%22">Yu H</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Mao+M%22">Mao M</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xu+R%22">Xu R</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Jia+S%22">Jia S</searchLink>; Key Laboratory for Animal Disease Control and Pharmaceutical Development of Heilongjiang Province, Northeast Agricultural University, Harbin, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.; College of Animal Science, Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, College of Veterinary Medicine, Zhejiang A&F University, Hangzhou, People's Republic of China.; College of Animal Science, Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%220113724%22">Journal of virology</searchLink> [J Virol] 2026 Jan 20; Vol. 100 (1), pp. e0164325. <i>Date of Electronic Publication: </i>2025 Dec 09.
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        Value: 10.1128/jvi.01643-25
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