Elevated lactate in AML bone marrow contributes to macrophage polarization via GPR81 signaling.
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| Title: | Elevated lactate in AML bone marrow contributes to macrophage polarization via GPR81 signaling. |
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| Authors: | Soto CA; Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine, Rochester, NY.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY., Lesch ML; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Department of Microbiology and Immunology, University of Rochester School of Medicine, Rochester, NY., Becker JL; Genomics Research Center, University of Rochester Medical Center, Rochester, NY., Sharipol A; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Department of Biomedical Engineering, University of Rochester School of Medicine, Rochester, NY., Khan A; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Department of Microbiology and Immunology, University of Rochester School of Medicine, Rochester, NY., Schafer XL; Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY., Li Z; Department of Microbiology and Immunology, University of Rochester School of Medicine, Rochester, NY., Streeter AR; Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine, Rochester, NY., Becker MW; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Department of Medicine, University of Rochester School of Medicine, Rochester, NY., Munger JC; Department of Microbiology and Immunology, University of Rochester School of Medicine, Rochester, NY.; Department of Biochemistry and Biophysics, University of Rochester School of Medicine, Rochester, NY., Frisch BJ; Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine, Rochester, NY.; Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY.; Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY.; Department of Biomedical Engineering, University of Rochester School of Medicine, Rochester, NY. |
| Source: | Blood advances [Blood Adv] 2026 Mar 10; Vol. 10 (5), pp. 1614-1629. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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